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dc.contributor.authorSOUZA, B. M. P. da S.pt_BR
dc.contributor.authorLAMBERT, S. M.pt_BR
dc.contributor.authorNISHI, S. M.pt_BR
dc.contributor.authorBENAVIDES, M. V.pt_BR
dc.contributor.authorBERNE, M. E. A.pt_BR
dc.contributor.authorMADRUGA, C. R.pt_BR
dc.contributor.authorALMEIDA, M. A. O. dept_BR
dc.date.accessioned2016-02-16T11:11:11Zpt_BR
dc.date.available2016-02-16T11:11:11Zpt_BR
dc.date.created2016-02-16pt_BR
dc.date.issued2015pt_BR
dc.identifier.citationRevista Brasileira de Parasitologia Veterinária, Jaboticabal, v. 24, n. 3, p. 317-323, jul./set. 2015.pt_BR
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1037115pt_BR
dc.descriptionGalectins and collectins are proteins classi!ed in the lectin family that have the ability to recognize molecular patterns associated with pathogens. Studies on cattle have demonstrated high expression of these proteins during infection with gastrointestinal nematodes. "e aim of this study was to investigate whether the level of Haemonchus contortus infection would alter the expression of galectins (Gal11 and Gal14) and collectins (SPA and CGN) in sheep. Twelve Corriedale sheep exposed to natural infection with nematodes were divided into two groups: group 1 (G1, n = 7) and group 2 (G2, n = 5), with low and high parasite burdens, respectively, based on fecal egg counts and abomasal parasite counts. The fecal egg counts and abomasal parasite counts were signi!cantly di#erent (p < 0.05) between the groups. Galectin and collectin gene expression was observed in all sheep abomasal samples. However, animals with lower infection levels showed lower expression of the genes Gal14, SPA and CGN (p < 0.05). Expression of lectins was associated with the abomasal H. contortus burden, thus suggesting that these proteins may have a role in controlling of this infection.pt_BR
dc.language.isoengeng
dc.rightsopenAccesseng
dc.subjectPequenos ruminantespt_BR
dc.subjectPCRpt_BR
dc.titleGalectins and collectinis expression are increased in Haemonchus contortus-infected corriedale sheep.pt_BR
dc.typeArtigo de periódicopt_BR
dc.date.updated2016-02-16T11:11:11Zpt_BR
dc.subject.thesagroLectinapt_BR
dc.subject.thesagroHelmintopt_BR
dc.subject.thesagroImunidadept_BR
dc.subject.thesagroRuminantept_BR
dc.subject.thesagroOvelhapt_BR
dc.subject.nalthesaurusInnate immunitypt_BR
dc.subject.nalthesaurusLectinspt_BR
dc.subject.nalthesaurusHelminthspt_BR
dc.subject.nalthesaurusSmall ruminantspt_BR
dc.subject.nalthesaurusSheeppt_BR
riaa.ainfo.id1037115pt_BR
riaa.ainfo.lastupdate2016-02-16pt_BR
dc.identifier.doi10.1590/S1984-29612015056pt_BR
dc.contributor.institutionUFBA; SABRINA MOTA LAMBERT, UFBA; SANDRA MAYUMI NISHI, UFBA; MAGDA VIEIRA BENAVIDES, CNPASA; MARIA ELISABETH AIRES BERNE, UFPEL; CLAUDIO ROBERTO MADRUGA, UFBA; MARIA ANGELA ORNELAS DE ALMEIDA, UFBA.pt_BR
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