Use este identificador para citar ou linkar para este item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1085814
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dc.contributor.authorPEREIRA, M. C.
dc.contributor.authorOLIVEIRA, D. A.
dc.contributor.authorHILL, L. E.
dc.contributor.authorZAMBIAZI, R. C.
dc.contributor.authorBORGES, C. D.
dc.contributor.authorVIZZOTTO, M.
dc.contributor.authorMERTENS-TALCOTT, S.
dc.contributor.authorTALCOTT, S.
dc.contributor.authorGOMES, C. L.
dc.date.accessioned2018-01-18T22:20:24Z-
dc.date.available2018-01-18T22:20:24Z-
dc.date.created2018-01-18
dc.date.issued2018
dc.identifier.citationFood Chemistry, v. 240, p. 396-404, 2018.
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1085814-
dc.descriptionGuabiroba fruit has been highlighted for its high phytochemical content, particularly of phenolic compounds. The stability, bioavailability, and bioactivity of these compounds can be enhanced by nanoencapsulation, to improve functionality. Poly (D,L-lactic-co-glycolic) acid (PLGA) nanoparticles containing phenolic extract of guabiroba (GPE) were synthesized by an adapted emulsion-evaporation method and their physico-chemical and functional properties were studied at two lactic to glycolic acid ratios (50:50 and 65:35). Higher (P < 0.05) or equivalent antioxidant capacity compared to free GPE were observed for GPE-loaded nanoparticles. Free extract and PLGA nanoparticles were effective inhibitors of Listeria innocua, with lower (P < 0.05) GPE concentrations required for inhibition when nanoencapsulated. Also, reduction of ROS generation in non-cancer cells was achieved with lower GPE concentrations (P < 0.05) after encapsulation. These results suggest that PLGA nanoparticles can be used as a delivery system for phenolic compounds at lower levels than originally required for enhanced functional properties.
dc.language.isoengeng
dc.rightsopenAccesseng
dc.titleEffect of nanoencapsulation using PLGA on antioxidant and antimicrobial activities of guabiroba fruit phenolic extract.
dc.typeArtigo de periódico
dc.date.updated2018-10-29T11:11:11Zpt_BR
dc.subject.thesagroGuabiroba
dc.subject.thesagroFrutapt_BR
riaa.ainfo.id1085814
riaa.ainfo.lastupdate2018-10-29 -03:00:00
dc.contributor.institutionMARINA C. PEREIRA, UFPEL; DANIELA A. OLIVEIRA, Texas A & M Universit; LAURA E. HILL, Texas A & M Universit; RUI CARLOS ZAMBIAZI, UFPEL; CAROLINE D. BORGES, UFPEL; MARCIA VIZZOTTO, CPACT; SUSANNE MERTENS-TALCOTT, Texas A & M Universit; STEPHEN TALCOTT, Texas A & M Universit; CARMEN L. GOMES, Texas A & M Universit.
Aparece nas coleções:Artigo em periódico indexado (CPACT)

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