Título:	A single dose of purple grape juice improves physical performance and antioxidant activity in runners: a randomized, crossover, double?blind, placebo study.
Autoria:	TOSCANO, L. de L. T. SILVA, A. S. FRANÇA, A. C. L. de SOUSA, B. R. V. de ALMEIDA FILHO, E. J. B. de COSTA, M. da S. BIASOTO, A. C. T. SILVA, D. F. da SENA, K. de F. CERQUEIRA, G. S. GONÇALVES, M. da C. R.
Afiliação:	Lydiane de Lima Tavares Toscano; Alexandre Sérgio Silva; Ana Carla Lima de França; Bruno Rafael Virgínio de Sousa; Eder Jackson Bezerra de Almeida Filho; Matheus da Silveira Costa; ALINE TELLES BIASOTO MARQUES, CPATSA; Darcilene Fiuza da Silva; Klécia de Farias Sena; Gilberto Santos Cerqueira; Maria da Conceição Rodrigues Gonçalves.
Ano de publicação:	2019
Referência:	European Journal of Nutrition, v. 58, nov. 2019.
Conteúdo:	PurposeTo investigate the effects of a single dose of juice on physical performance, oxidative stress, inflammation and muscle damage in runners.Methods Fourteen recreational male runners (39 ± 9 years, VO2peak = 55.9 ± 6.5 ml/kg/min) performed two running tests to exhaustion at 80% of VO2max after ingesting grape juice or a placebo drink (10 ml/kg/day) randomly. Blood samples were taken before and 2 h after supplementation and immediately after running to analyze total antioxidant capacity (TAC), malondialdehyde (MDA), alpha-1 acid glycoprotein (A1GPA), high-sensitivity C-reactive protein (hs-CRP), creatine kinase (CK) and lactate dehydrogenase (LDH).ResultsThe participants ran for an average of 59.2 ± 27.8 min until exhaustion in the placebo group and for 68.4 ± 29.7 min until exhaustion in the grape juice intake group, which was a significantly longer time (p = 0.008). This improvement in physical performance was accompanied by a 43.6% increase in TAC (p = 0.000) at the post-exercise timepoint compared to the level at baseline. MDA, A1GPA, hs-CRP, CK, and LDH did not exhibit changes. In contrast, no significant change in any variable was observed after consuming the placebo drink.ConclusionThe single-dose intake of purple grape juice demonstrated an ergogenic effect in recreational runners by increas-ing run time to exhaustion and increasing antioxidant activity.
Thesagro:	Nutrição Uva Dieta
NAL Thesaurus:	Polyphenols Oxidative stress Athletic performance
Palavras-chave:	Sumo de uva roxa Desempenho físico Atividade antioxidante
ISSN:	1436-6207
Digital Object Identifier:	0.1007/s00394-019-02139-6
Tipo do material:	Artigo de periódico
Acesso:	openAccess
Aparece nas coleções:	Artigo em periódico indexado (CPATSA)