Title:	Hematology, clinical biochemistry, and blood cell morphology features of captive bothrops jararaca from Southeast Brazil.
Authors:	ALCANTARA, A. O. REIS, B. M. M. FONSECA, J. G. SOUSA, M. A. C. ROXO, V. H. A. SOUZA, G. J. CASTRO, F. de F. A. SOUZA, G. N. de FERNANDES, J. LEMOS, E. R. S. SOUZA, A. M.
Affiliation:	AMANDA O. ALCANTARA, UNIVERSIDADE FEDERAL FLUMINENSE; BIANCA M. M. REIS, INSTITUTO VITAL BRAZIL; JULIANA G. FONSECA, INSTITUTO VITAL BRAZIL; MAÍRA A. C. SOUSA, UNIVERSIDADE FEDERAL FLUMINENSE; VITOR HUGO A. ROXO, INSTITUTO VITAL BRAZIL; GUILHERME J. SOUZA, INSTITUTO VITAL BRAZIL; FÚLVIA DE FÁTIMA A. CASTRO, UNIVERSIDADE FEDERAL DE JUIZ DE FORA; GUILHERME NUNES DE SOUZA, CNPGL; JORLAN FERNANDES, INSTITUTO OSWALDO CRUZ; ELBA REGINA S. LEMOS, INSTITUTO OSWALDO CRUZ; ALINE M. SOUZA, UNIVERSIDADE FEDERAL FLUMINENSE.
Date Issued:	2025
Citation:	Veterinary Clinical Pathology, 2025.
Description:	Background: Snakebite envenomation is a worldwide public health issue, particularly relevant to low and middle-income countries. Bothrops spp. antivenom is needed for snakebite treatment, which requires the maintenance of healthy snakes in captivity. Hematology and clinical biochemistry are important tools for monitoring the health status of these animals, as well as detecting hemoparasites (i.e., Hepatozoon spp.). Objectives: This study aims to establish hematologic and biochemical reference intervals in a population of captive B. jararaca in a Brazilian serpentarium and assess blood cell morphology. Methods: Blood samples of 32 specimens of captive B. jararaca were collected and analyzed for complete blood count and biochemical variables, such as total proteins, albumin, cholesterol, triglycerides, calcium, phosphorus, urea, creatinine, uric acid, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, gamma-glutamyl transferase, and creatine kinase. Blood smears were also evaluated to investigate blood parasites. Each variable was statistically analyzed according to the ASVCP guidelines and compared between sexes and the occurrence of Hepatozoon spp. Results: This study establishes the hematology and clinical biochemistry reference intervals and describes B. jararaca blood cell morphology. We observed no differences between sexes. Conclusions: Our study provides the first reference intervals for hematologic and biochemical variables for B. jararaca on the basis of ASCVP recommendations. The RI described could be essential for the management and treatment of B. jararaca kept under similar captive conditions.
Thesagro:	Cobra Veneno Saúde Pública Antídoto
Keywords:	Jararaca Hemoparasita
DOI:	https://doi.org/10.1111/vcp.70032
Notes:	First online.
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CNPGL)