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dc.contributor.authorCUNICO, M. M.pt_BR
dc.contributor.authorAUER, C. G.pt_BR
dc.contributor.authorLIMA, C. P. dept_BR
dc.contributor.authorCÔCCO, L. C.pt_BR
dc.contributor.authorYAMAMOTO, C. I.pt_BR
dc.contributor.authorMIGUEL, M. D.pt_BR
dc.contributor.authorMIGUEL, O. G.pt_BR
dc.contributor.authorSANQUETTA, C. R.pt_BR
dc.date.accessioned2013-03-04T11:11:11Zpt_BR
dc.date.available2013-03-04T11:11:11Zpt_BR
dc.date.created2013-03-04pt_BR
dc.date.issued2012pt_BR
dc.identifier.citationRevista de Ciências Farmacêuticas Básica e Aplicada, v. 33, n. 4, p. 515-519, 2012.pt_BR
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/952025pt_BR
dc.descriptionOttonia martiana Miq. (Piperaceae), a plant known popularly in southern Brazil as “anestésia” and used in the treatment of odontalgia for its anesthetic action on the oral mucosa, was investigated for antibacterial activity by paper disc agar diffusion and bioautographic methods, against microorganisms present in the human oral cavity [Streptococcus mutans (ATCC 25175), Streptococcus mitis (ATCC 49456), Streptococcus pyogenes (ATCC 19615), Streptococcus salivarius (ATCC 25975), Escherichia coli (ATCC 11229 and 25922), Pseudomonas aeruginosa (ATCC 27853) and Enterobacter aerogenes (ATCC 27853).The crude extract of O. martiana (32.9 mg mL-1) had antibacterial potential against all Gram-positive bacteria tested. Analysis of the bioautograms led to the detection of bioactive substances, among which it was possible to identify piperovatine (Rf 0.35), piperlonguminine (Rf 0.52) and isopiperlonguminine (Rf 0.52). The piperovatine and isopiperlonguminine were isolated from the roots of O. martiana, guided by a bioautographic antibacterial bioassay.pt_BR
dc.language.isoengeng
dc.rightsopenAccesseng
dc.subjectAtividade antibacterianapt_BR
dc.subjectDor de dentept_BR
dc.subjectOttonia martianapt_BR
dc.titleBioautography to assess antibacterial activity of Ottonia martiana Miq. (Piperaceae) on the human oral microbiota.pt_BR
dc.typeArtigo de periódicopt_BR
dc.date.updated2015-02-19T11:11:11Zpt_BR
dc.subject.thesagroAmidopt_BR
riaa.ainfo.id952025pt_BR
riaa.ainfo.lastupdate2015-02-19pt_BR
dc.contributor.institutionMIRIAM MACHADO CUNICO, UFPR; CELSO GARCIA AUER, CNPF; CRISTINA PEITZ DE LIMA, UFPR; LILIAN CRISTINA CÔCCO, UFPR; CARLOS ITSUO YAMAMOTO, UFPR; MARILIS DALLARMI MIGUEL, UFPR; OBDULIO GOMES MIGUEL, UFPR; CARLOS ROBERTO SANQUETTA, UFPR.pt_BR
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