Use este identificador para citar ou linkar para este item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/960605
Registro completo de metadados
Campo DCValorIdioma
dc.contributor.authorFERREIRA, L. E.
dc.contributor.authorCASTRO, P. M. N.
dc.contributor.authorCHAGAS, A. C. de S.
dc.contributor.authorFRANÇA, S. C.
dc.contributor.authorBELEBONI, R. O.
dc.date.accessioned2023-05-12T20:47:14Z-
dc.date.available2023-05-12T20:47:14Z-
dc.date.created2013-06-26
dc.date.issued2013
dc.identifier.citationExperimental Parasitology, v. 134, n. 3, p. 327-332, 2013.
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/960605-
dc.descriptionDespite the overall progress of sheep farming in Brazil, infections with the gastrointestinal parasite Haemonchus contortus represent one the most important problems in sheep production, aggravated by the increasing resistance of nematodes to traditional anthelmintic drugs caused by inadequate sheep flock management by breeders. Ethnopharmacological data indicate Annona muricata as a promising alternative for the control of gastrointestinal nematodes because of its general anthelmintic properties. The aim of this work was to evaluate the in vitro anthelmintic effects of A. muricata aqueous leaf extract against eggs, infective larvae and adult forms of parasitic nematode H. contortus. At higher doses, A. muricata extract showed 84.91% and 89.08% of efficacy in egg hatch test (EHT) and larval motility test (LMT), respectively. In the adult worm motility test, worms were completely immobilized within the first 6-8 h of nematode exposition to different dilutions of extract. Phytochemical analysis indicated the presence of phenolic compounds in A. muricata aqueous leaf extract that may be responsible for the anthelmintic effects observed. Moreover those results validate the traditional use of A. muricata as a natural anthelmintic and then the pharmacological potential of its compounds for future in vivo investigations.
dc.language.isoeng
dc.rightsopenAccess
dc.subjectA muricata
dc.subjectAnthelmintics Gastrointestinal nematodes
dc.subjectH contortus
dc.titleIn vitro anthelmintic activity of aqueous leaf extract of Annona muricata L. (Annonaceae) against Haemonchus contortus from sheep.
dc.typeArtigo de periódico
dc.subject.nalthesaurusmedicinal plants
dc.subject.nalthesaurusphytotherapy
riaa.ainfo.id960605
riaa.ainfo.lastupdate2023-05-12
dc.identifier.doi10.1016/j.exppara.2013.03.032
dc.contributor.institutionL. E. FERREIRA, Universidade de Ribeirão Preto; P. M. N. CASTRO, Universidade de Ribeirão Preto; ANA CAROLINA DE SOUZA CHAGAS, CPPSE; S. C. FRANÇA, Universidade de Ribeirão Preto; R. O. BELEBONI, Universidade de Ribeirão Preto.
Aparece nas coleções:Artigo em periódico indexado (CPPSE)

Arquivos associados a este item:
Arquivo TamanhoFormato 
PROCI-2013.00032.pdf880,59 kBAdobe PDFVisualizar/Abrir
Mostrar registro simples do item Visualizar estatísticas

FacebookTwitterDeliciousLinkedInGoogle BookmarksMySpace