Use este identificador para citar ou linkar para este item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/974748
Registro completo de metadados
Campo DCValorIdioma
dc.contributor.authorGIACHETTO, P. F.pt_BR
dc.contributor.authorPEREIRA, F. C. P.pt_BR
dc.contributor.authorMOKRY, F. B.pt_BR
dc.contributor.authorHIGA, R. H.pt_BR
dc.contributor.authorMUDADU, M. A.pt_BR
dc.contributor.authorSILVA, M. V.pt_BR
dc.contributor.authorNICIURA, S. C. M.pt_BR
dc.contributor.authorCARDOSO, F. F.pt_BR
dc.contributor.authorALENCAR, M. M.pt_BR
dc.contributor.authorMEIRELLES, S. L. C.pt_BR
dc.contributor.authorLIMA, A. O.pt_BR
dc.contributor.authorREGITANO, L. C. A.pt_BR
dc.date.accessioned2014-01-02T11:11:11Zpt_BR
dc.date.available2014-01-02T11:11:11Zpt_BR
dc.date.created2014-01-02pt_BR
dc.date.issued2013pt_BR
dc.identifier.citationIn: INTERNATIONAL PLANT & ANIMAL GENOME, 21., 2013, San Diego. [Abstracts...]. [S.l.: s.n.], 2013.pt_BR
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/974748pt_BR
dc.descriptionGenomic structural variation, in the form of large-scale insertions and deletions, as well as inversions and translocations, are referred to as copy number variations (CNVs). Compared to single nucleotide polymorphisms (SNPs), CNVs have potentially greater effects on gene structure, dosage and regulation, being an important source of phenotypic variation. In humans, CNVs are widespread in the genome and have been shown to be associated with complex traits. In livestock species, the characterization of this genetic variation is an important step toward linking genes or genomic regions with phenotypic traits of economic importance. Studies in cattle have revealed some CNVs associated with differences in host parasite resistance and breed-specific differences in adaptation, health, and production traits. We report initial data from an analysis of CNVs in Canchim, a synthetic cattle (5/8 Charolais + 3/8 Zebu) that has been selected for meat production in Brazil. Using the PennCNV software and data from 192 Canchim DNA samples with extreme phenotypes for ribeye area, genotyped with Illumina BovineHD BeadChip, a total of 6,985 CNVs were detected. The regions ranged from 20,012bp to 4,157,122bp, with mean and median of 140,484bp and 81,303bp, respectively. Copy number gains (62.09%) were found to be more common than deletions. Gene content of discovered CNVs and functional enrichment analysis are being assessed using Ensembl genes and cattle RefSeq databases, and PANTHER classification system, respectively. We expect to use these findings in genome wide association studies to better understand the genetic variation underlying meat quality in beef cattle.pt_BR
dc.language.isoengeng
dc.rightsopenAccesseng
dc.subjectPolimorfismo de nucleotídeo únicopt_BR
dc.subjectBioinformáticapt_BR
dc.subjectCopy number variationspt_BR
dc.titleInitial analysis of copy number variations in canchim beef cattle with extreme phenotypes for ribeye area.pt_BR
dc.typeResumo em anais e proceedingspt_BR
dc.date.updated2020-01-22T11:11:11Zpt_BR
dc.subject.thesagroVariação Genéticapt_BR
dc.subject.nalthesaurusGenetic variationpt_BR
dc.subject.nalthesaurusBioinformaticspt_BR
dc.subject.nalthesaurusSingle nucleotide polymorphismeng
dc.description.notesPôster P0572.pt_BR
dc.format.extent2Não paginado.pt_BR
riaa.ainfo.id974748pt_BR
riaa.ainfo.lastupdate2020-01-22 -02:00:00pt_BR
dc.contributor.institutionPOLIANA FERNANDA GIACHETTO, CNPTIA; FERNANDA C. P. PEREIRA; FABIANA B. MOKRY; ROBERTO HIROSHI HIGA, CNPTIA; MAURICIO DE ALVARENGA MUDADU, CPPSE; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; SIMONE CRISTINA MEO NICIURA, CPPSE; FERNANDO FLORES CARDOSO, CPPSUL; MAURICIO MELLO DE ALENCAR, CPPSE; SARAH L. C. MEIRELLES, UFV; ANDRESSA O. LIMA, UFSCar; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.pt_BR
Aparece nas coleções:Resumo em anais de congresso (CNPTIA)

Arquivos associados a este item:
Arquivo TamanhoFormato 
P0572.odt193,48 kBOpenDocument TextVisualizar/Abrir
Mostrar registro simples do item Visualizar estatísticas

FacebookTwitterDeliciousLinkedInGoogle BookmarksMySpace