Título:	Ecotoxicity evaluation: preparation of poly-E-caprolactone and chitosan nanoparticles as carriers of thiametoxam pesticide.
Autoria:	ASSALIN, M. R. SOUZA, D. R. C. de ROSA, M. A. DUARTE, R. C. R. M. DONAIRE, P. DURAN, N.
Afiliação:	MARCIA REGINA ASSALIN, CNPMA; DEBORA RENATA CASSOLI DE S DUTRA, CNPMA; MARIA APARECIDA ROSA, CNPMA; R. C. R. M. Duarte; Patricia P. R. Donaire, Center of Natural and Human Sciences, Universidade Federal do ABC, Santo Andre, SP; Nelson Duran, Laboratory of Urogenital Carcinogenesis and Immunotherapy, Department of Structural and Functional Biology/UNICAMP; NanoBioss, Institute of Chemistry/UNICAMP; Nanomedicine Research Unit/UFABC.
Ano de publicação:	2018
Referência:	In: INTERNATIONAL CONFERENCE ON HEALTH AND SAFETY ISSUES RELATED TO NANOMATERIALS FOR A SOCIALLY RESPONSIBLE APPROACH - NANOSAFE, 6., 2018, Grenoble. Book of Abstracts... Grenoble: 2018. Ref. A91473MA.
Páginas:	p. 198.
Conteúdo:	Huanglongbing (HLB) is probably the most serious disease of citrus, nowadays. The severity of disease is mainly the rapid and efficient dissemination of the bacteria associated with HLB by psyllids Diaphorina citri (D. citri) and the absence of genetic resistance in citrus. Chemical control is the main way to control the psyllids, and there are different insecticides registered for this purpose. Thiamethoxam (neonicotinoid insecticide) is one of the active ingredients used in the control of HLB. Pesticide formulations nanocapsules allow a controlled release of active as well as protection against their premature degradation, allowing the use of conventional insecticide in a more sustainable way. Thus, studies of the effectiveness of encapsulated pesticide formulations are extremely important for enabling its use in agriculture. This study reports the encapsulation of the insecticide thiamethoxam in polymeric particles from poly-?-caprolactone (PCL) and chitosan by double emulsion and solvent evaporation method using different concentrations of chitosan and two Pluronic (poloxamer) copolymers, F 127 and F68. These nanoparticles were characterized in terms of size, polydispersity, and encapsulation efficiency. The microalgae Pseudokirchneriella subcapitata (bioindicator chloroficea) was used to evaluate to ecotoxicity of nanopesticide in comparation of commercial formulation. The nanopesticide obtained resulted in homogeneous and monodisperse particles, with the mean diameter obtained of 166.3 nm, polydispersity indices were lower than 0.4 and positive superficial charge (+25 mv).The encapsulation efficiency, measured by by liquid chromatography, it was 34%. The ecotoxicity results demonstrated that the nanopesticide was less toxic that commercial formulations, in the same concentrations.
Thesagro:	Toxicologia Pesticida
Palavras-chave:	HBL
Tipo do material:	Resumo em anais e proceedings
Acesso:	openAccess
Aparece nas coleções:	Resumo em anais de congresso (CNPMA)