Title:	Separation of antbacterial biocompounds from Hancorni speciosa leaves by a sequential process of pressurized liquid extraction.
Authors:	BARBOSA, A. M. SANTOS, K. S. BORGES, G. R. MUNIZ, A. V. C. da S. MENDONCA, F. M. R. PINHEIRO, M. S. FRANCESCHI, E. DARIVA, C. PADILHA, F. F.
Affiliation:	ADRIELE M. BARBOSA; KLEBSON S. SANTOS; GUSTAVO R. BORGES; ANA VERUSKA CRUZ DA SILVA MUNIZ, CPATC; FLAVIA M. R. MENDONCA; MALONE S. PINHEIRO; ELTON FRANCESCHI; CLAUDIO DARIVA; FRANCINE F. PADILHA.
Date Issued:	2019
Citation:	Separation and Purification Technology, n. 222, p. 390-395, 2019.
Description:	Hancornia speciosahas bioactive molecules such as phenolic compounds which exhibit antioxidant and anti-microbial properties. Nevertheless, the separation of these substances from a medicinal plant can be differentaccording to the extraction process and solvent used. Thus, the present study aimed was to separate phenoliccompounds fromHancornia speciosaleaves in three steps by using a sequential pressurized liquid extraction andevaluated their antioxidant and antibacterial activity. Results showed that the temperature increase from 25 to60° C provides a significative enhancement in the extraction yield. The raw ethanol extract (39.0 ± 0.2%)showed the highest overall extraction yield. However, fractionated ethanol extract (FEE) at 60 °C exhibited thehighest amount of total phenolic compounds (347.0 ± 4.12 mg/g extract). Fractionated ethyl acetate extract(FAE) at 60 °C presented improved quantity of totalflavonoids (230.4 ± 3.5 mg/g extract) and rutin content(16.6 ± 0.3 mg/mL extract). The antioxidant activity results for IC50of DPPH indicated that FEE(3.8 ± 0.1 ?g/mL) was the best free radical scavenger. FAE and FEE were able to inhibit the growth of mul-tidrug-resistantE. coli.
Thesagro:	Fruta Tropical Mangaba Hancornia Speciosa
NAL Thesaurus:	Tropical and subtropical fruits
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CPATC)