Title:	Biodegradable Mats for the Design of Bifunctional Biosensors for Glucose Detection in Urine.
Authors:	GOMES, N. O. PASCHOALIN, R. T. BILLATO, S. SORIGOTTI, A. R. FARINAS, C. S. MATTOSO, L. H. C. MACHADO, S. A. S. OLIVEIRA JR, O. N. RAYMUNDO-PEREIRA, P. A.
Affiliation:	CRISTIANE SANCHEZ FARINAS, CNPDIA; LUIZ HENRIQUE CAPPARELLI MATTOSO, CNPDIA.
Date Issued:	2023
Citation:	Engineering Proceedings, v. 35, n. 1, 2023.
Pages:	8 p.
Description:	Abstract: We introduce a bifunctional architecture to construct biosensors on solution-blow spinning fiber mats of polylactic acid (PLA) and polyethylene glycol (PEG). PLA/PEG mats acted as substrate for printing electrodes and as matrix to immobilize glucose oxidase (GOx). Prussian Blue nanoparticles (PB) decorated working electrodes to detect H2O2 from enzymatic catalysis at a low applied potential (0 V vs Ag/AgCl) with detection limit of 0.197 mM. The inexpensive bifunctional device (<US $0.25 per unit) exhibited a rapid response, long lifetime and performance similiar to the standard method for glucose monitoring in human urine samples. The PLA/PEG mats are sustainable alternative for biosensing and wearable applications.
Keywords:	Biosensor Screen-printed electrodes Prussian blue Non-invasive Sustainable substrates
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CNPDIA)