Title:	Unraveling the antifungal composition of bitter orange decoction against the melon pathogen Fusarium jinanense .
Authors:	FREITAS, M. D. de LIMA JUNIOR, R. D. SILVA, F. E. F. da INOKUTI, E. M. OSTER, A. H. ZAMPIERI, D. LIMA, C. S. FILL, T. P. LEMOS, T. L. G. de
Affiliation:	MARIA DAIANE DE FREITAS, UNIVERSIDADE FEDERAL DO CEARA; RODOLFO DANTAS LIMA JUNIOR, UNIVERSIDADE DE CAMPINAS; FRANCISCO ERIVALDO FREITAS DA SILVA, UNIVERSIDADE FEDERAL DO CEARA; ELIANE MAYUMI INOKUTI, UNIVERSIDADE FEDERAL DO CEARA; ANDREIA HANSEN OSTER, CNPUV; DAVILA ZAMPIERI, UNIVERSIDADE FEDERAL DO CEARA; CRISTIANO SOUZA LIMA, UNIVERSIDADE FEDERAL DO CEARA; TAICIA PACHECO FILL, UNIVERSIDADE DE CAMPINAS; TELMA LEDA GOMES DE LEMOS, UNIVERSIDADE FEDERAL DO CEARA.
Date Issued:	2024
Citation:	Food Chemistry, v. 455, n. 139769, 2024.
Description:	Bitter orange (Citrus aurantium) is an important source of essential oils with high antimicrobial activities, however the composition and antifungal potential of the decoction peels is little explored. This study assessed the peel decoction’s chemical profile at the secondary metabolism level and its antifungal activity against the melon phytopathogen Fusarium jinanense. The decoction’s antifungal potential was investigated using a bioassay-guided fractionation approach based on Solid-Phase Extraction (SPE) and LC-HRMS/MS analysis. Coumarins and flavones were the most abundant classes of compounds in the high-value fractions responsible for up to 61% of the mycelial inhibition of F. jinanense. Overall, this study has presented for the first time the chemical composition, the antifungal potential of the decoction of C. aurantium peels and the compounds associated with these results. This strategy can guide the exploration of under-explored food sources and add value to compounds or fractions enriched with bioactive compounds.
Thesagro:	Citrus Aurantium
NAL Thesaurus:	Phenolic compounds
Keywords:	Molecular networking SIRIUS Anti-phytopathogenic activity Fusarium rot melon
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CNPUV)