Title:	Arsenic bioaccumulation and biotransformation in different tissues of Nile tilapia (Oreochromis niloticus): a comparative study between As(III) and As(V) exposure and evaluation of antagonistic effects of selenium.
Authors:	FERREIRA, N. DOS S. COSTA, P. H. DA SÁ, I. P. DE BERNARDO, V. S. TORRES, F. F. FIGUEIREDO, J. G. AMARAL, C. D. B. DO NOGUEIRA, A. R. de A. SILVA, D. G. H. DA GONZALEZ, M. H.
Affiliation:	NATHALIA DOS SANTOS FERREIRA, UNIVERSIDADE ESTADUAL PAULISTA PEDRO HENRIQUE DA COSTA, UNIVERSIDADE ESTADUAL PAULISTA ÍVERO PITA DE SÁ VICTORIA SIMÕES BERNARDO, UNIVERSIDADE ESTADUAL PAULISTA FLAVIENE FELIX TORRES, UNIVERSIDADE ESTADUAL PAULISTA JOZI GODOY FIGUEIREDO, UNIFASIPE CLARICE DIAS BRITTO DO AMARAL, UNIVERSIDADE FEDERAL DO PARANÁ ANA RITA DE ARAUJO NOGUEIRA, CPPSE DANILO GRÜNIG HUMBERTO DA SILVA, UNIVERSIDADE ESTADUAL PAULISTA MARIO HENRIQUE GONZALEZ, UNIVERSIDADE ESTADUAL PAULISTA.
Date Issued:	2024
Citation:	Chemosphere, v. 359, July 2024, 142289.
Description:	The speciation of arsenic in fish has been widely investigated, but bioaccumulation and biotransformation of inorganic As in different tissues of Nile tilapia (Oreochromis niloticus) are not fully understood. The present study aimed to investigate the bioaccumulation of As in Nile tilapia, as well as to evaluate the distribution of the main arsenic species (As(III), As(V), MMA, DMA, and AsB) in liver, stomach, gill, and muscle, after controlled exposures to As(III) and As(V) at concentrations of 5.0 and 10.0 mg L−1 during periods of 1 and 7 days. Total As was determined by inductively coupled plasma mass spectroscopy (ICP-MS). For both exposures (As(III) and As(V)), the total As levels after 7-day exposure were highest in the liver and lowest in the muscle. Overall, the Nile tilapia exposed to As(III) showed higher tissue levels of As after the treatments, compared to As(V) exposure. Speciation of arsenic present in the tissues employed liquid chromatography coupled to ICP-MS (LC-ICP-MS), revealing that the biotransformation of As included As(V) reduction to As(III), methylation to monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA), and subsequent conversion to nontoxic arsenobetaine (AsB), which was the predominant arsenic form. Finally, the interactions and antagonistic effects of selenium in the bioaccumulation processes were tested by the combined exposure to As(III), the most toxic species of As, together with tetravalent selenium (Se(IV)). The results indicated a 4–6 times reduction of arsenic toxicity in the tilapia.
Thesagro:	Tilápia
NAL Thesaurus:	Fish
Keywords:	Speciation Arsenic species Selenium antagonism LC ICP MS ICP MS
DOI:	https://doi.org/10.1016/j.chemosphere.2024.142289
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CPPSE)