Title:	In vitro cytocidal effects of the essential oil from Croton cajucara (red sacaca) and its major constituent 7- hydroxycalamenene against Leishmania chagasi.
Authors:	RODRIGUES, I. A. AZEVEDO, M. M. B. CHAVES, F. C. M. BIZZO, H. R. CORTE-REAL, S. ALVIANO, D. S. ALVIANO, C. S. ROSA, M. S. S. VERMELHO, A. B.
Affiliation:	IGOR A. RODRIGUES, UFRJ; MARIANA M. B. AZEVEDO, UFRJ; FRANCISCO CELIO MAIA CHAVES, CPAA; HUMBERTO RIBEIRO BIZZO, CTAA; Suzana Corte-Real, Instituto Oswaldo Cruz; Daniela S. Alviano, UFRJ; Celuta S Alviano, UFRJ; Maria S S Rosa, UFRJ; Alane B. Vermelho, UFRJ.
Date Issued:	2013
Citation:	BMC Complementary and Alternative Medicine, v. 13, n. 1, p. 249, Oct. 2013.
Description:	Visceral leishmaniasis is the most serious form of leishmaniasis and can be lethal if left untreated. Currently available treatments for these parasitic diseases are frequently associated to severe side effects. The leaves of Croton cajucara are used as an infusion in popular medicine to combat several diseases. Previous studies have demonstrated that the linalool-rich essential oil from C. cajucara (white sacaca) is extremely efficient against the tegumentary specie Leishmania amazonensis. In this study, we investigated the effects of the 7-hydroxycalamenene-rich essential oil from the leaves of C. cajucara (red sacaca) against Leishmania chagasi, as well as on the interaction of these parasites with host cells.
Keywords:	Sacaca
DOI:	10.1186/1472-6882-13-249
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CPAA)