Embrapa Suínos e Aves (CNPSA) https://www.alice.cnptia.embrapa.br/alice/handle/item/37 2026-07-20T04:46:29Z 2026-07-20T04:46:29Z SCHMIDT, G. S. ABREU, P. G. de RAMOS, E. J. N. HELING, L. R. MAGRO, A. O. BACH, D. L. G. https://www.alice.cnptia.embrapa.br/alice/handle/doc/1188303 2026-07-19T14:51:44Z 2026-01-01T00:00:00Z

Título: Potencial da biotecnologia no controle de pragas na avicultura. Autoria: SCHMIDT, G. S.; ABREU, P. G. de; RAMOS, E. J. N.; HELING, L. R.; MAGRO, A. O.; BACH, D. L. G. Conteúdo: A avicultura é uma das fontes mais importantes na produção de proteína animal, alél de ser uma atividade relacionada ao desenvolvimento econômico e social de diversos países. Os modelos de produção atuais, favorecem a manifestação de algumas pragas, principalmente em função da intensificação estabelecida nos sistemas industrias. sem o devido controle populacional, a proliferação de pragas traz prejuízos técnicos e econômicos.

2026-01-01T00:00:00Z ALEGRIA, O. V. C. TORRES, M. C. BREYER, G. M. REBELATTO, R. WUADEN, C. R. PASTORE, J. LAZZAROTTI, M. RAMOS, R. T. J. DORN, M. KICH, J. D. SIQUEIRA, F. M. https://www.alice.cnptia.embrapa.br/alice/handle/doc/1188047 2026-07-12T16:46:00Z 2026-01-01T00:00:00Z

Título: Dynamics of bacterial communities and resistomes across swine waste stabilization ponds and fertilized soils. Autoria: ALEGRIA, O. V. C.; TORRES, M. C.; BREYER, G. M.; REBELATTO, R.; WUADEN, C. R.; PASTORE, J.; LAZZAROTTI, M.; RAMOS, R. T. J.; DORN, M.; KICH, J. D.; SIQUEIRA, F. M. Conteúdo: The environmental dissemination of antimicrobial resistance (AMR) through livestock waste represents a growing concern for human, environmental, and animal health. This study investigated how swine waste stabilization ponds (WSPs), and subsequent manure application to agricultural soils, influence bacterial community structure, antimicrobial resistance genes (ARGs), and mobile genetic elements (MGEs). Using shotgun metagenomics, we analyzed 80 samples from 20 swine farms, including waste collected before and after WSP treatment and soils with and without a history of manure application. Distinct microbial profiles were observed between waste and soil environments. Waste samples were dominated by Bacillota, Bacteroidota, and Pseudomonadota, whereas soils were enriched in Actinomycetota, particularly Streptomyces. WSP significantly reduced microbial diversity and caused shifts toward stress-tolerant taxa, indicating selective pressures during the process. Manure-fertilized soils exhibited altered community composition and enrichment of clinically relevant ARGs, including the fluoroquinolone resistance gene adeF. Waste management practices influenced resistome composition, with treated waste showing increased relative abundance of macrolide resistance genes (ermB and mefA). In soils, ARG profiles were associated with distinct MGE patterns, suggesting environment-specific mechanisms of gene mobility. Phage-associated elements were more prevalent in waste samples, whereas transposons were more prominent in soils, where ARG-MGE co-occurrence patterns indicated potential for horizontal gene transfer. Overall, our findings demonstrate that WSP management and soil application of swine manure shape both microbial communities and resistome configurations. These results underscore the importance of integrating waste treatment strategies into AMR surveillance frameworks and support a One Health approach to mitigate its dissemination in agroecosystems.

2026-01-01T00:00:00Z SILVEIRA, K. R. D. HAACH, V. BASTOS, A. P. A. https://www.alice.cnptia.embrapa.br/alice/handle/doc/1188057 2026-07-12T16:45:56Z 2026-01-01T00:00:00Z

Título: Genomic monitoring and engineering stable and safe immortalized cell platforms for industrial cellular agriculture. Autoria: SILVEIRA, K. R. D.; HAACH, V.; BASTOS, A. P. A. Conteúdo: Abstract: Cultivated-meat production relies on robust animal cell-line engineering, scalable tissue-engineering strategies, and clearly defined regulatory standards. This review examines the developmental pipeline from primary tissue biopsy to large-scale expansion and regulatory evaluation, focusing on stable and safe immortalized cell platforms. We compare muscle satellite cells, mesenchymal stromal/adipogenic progenitors and induced pluripotent stem cells, highlighting trade-offs among proliferative capacity, lineage commitment, genomic stability, and food-safety considerations. We then analyze immortalization strategies, including spontaneous senescence bypass, telomerase reactivation and CRISPR-based checkpoint modulation, highlighting their impact on genomic stability and food-safety risks. Recent advances in serum-free media, extracellular matrix-mimetic biomaterials and staged co-culture protocols have enabled centimeter-scale tissues with improved texture and marbling; however, cost, reproducibility and scalability remain bottlenecks. Integrating multi-omics surveillance with life-cycle assessment reveals that environmental benefits (land, water and antibiotic reduction) are attainable only when energy inputs and growth-factor sourcing are optimized. Finally, we examine regulatory frameworks that distinguish food-grade immortalized cells from pharmaceutical substrates and genetically modified crops. By integrating cell biology, animal biotechnology, and bioprocess engineering, this review identifies technical priorities for advancing cultivated meat from laboratory development to industrial implementation, positioning genomic monitoring as an essential framework for assessing biological stability, functional predictability, and food-production suitability.

2026-01-01T00:00:00Z SILVA, T. V. B SANTOS, M. C. P. SANTOS, P. A. BERTOL, T. M. SILVA, K. R. SILVA, R. C. FEITOSA, C. C. O. SILVA, C. M. https://www.alice.cnptia.embrapa.br/alice/handle/doc/1188033 2026-07-12T16:45:38Z 2026-01-01T00:00:00Z

Título: Parâmetros nutricionais e metabólicos do uso da farinha de vísceras para suínos em crescimento. Autoria: SILVA, T. V. B; SANTOS, M. C. P.; SANTOS, P. A.; BERTOL, T. M.; SILVA, K. R.; SILVA, R. C.; FEITOSA, C. C. O.; SILVA, C. M. Conteúdo: Apesar do amplo uso da farinha de vísceras de aves (FVA) na nutrição de suínos informações consistentes sobre a composição centesimal e teor de energia metabolizável corrigida para nitrogênio ainda são relevantes, por se tratar de um ingrediente alternativo. Nesse sentido, foi determinada a composição nutricional da FVA e realizado um ensaio de metabolismo no qual oito suínos em crescimento com o peso médio de 46 kg foram distribuídos em delineamento com blocos casualizados, a FVA foi adicionada em substituição a 20% da dieta referência.

2026-01-01T00:00:00Z