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dc.contributor.authorHONGO, J. A.pt_BR
dc.contributor.authorCASTRO, G. M. dept_BR
dc.contributor.authorCINTRA, L. C.pt_BR
dc.contributor.authorZERLOTINI, A.pt_BR
dc.contributor.authorLOBO, F. P.pt_BR
dc.date.accessioned2015-11-04T11:11:11Zpt_BR
dc.date.available2015-11-04T11:11:11Zpt_BR
dc.date.created2015-11-04pt_BR
dc.date.issued2015pt_BR
dc.identifier.citationBMC Genomics, London, v. 16, n. 1, 567, Aug. 2015.pt_BR
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1027912pt_BR
dc.descriptionAbstract: Background: Detection of genes evolving under positive Darwinian evolution in genome-scale data is nowadays a prevailing strategy in comparative genomics studies to identify genes potentially involved in adaptation processes. Despite the large number of studies aiming to detect and contextualize such gene sets, there is virtually no software available to perform this task in a general, automatic, large-scale and reliable manner. This certainly occurs due to the computational challenges involved in this task, such as the appropriate modeling of data under analysis, the computation time to perform several of the required steps when dealing with genome-scale data and the highly error-prone nature of the sequence and alignment data structures needed for genome-wide positive selection detection.pt_BR
dc.language.isoengeng
dc.rightsopenAccesseng
dc.subjectPotionpt_BR
dc.subjectEvolução Darwinianapt_BR
dc.subjectComparative genomicspt_BR
dc.subjectPositive selectionpt_BR
dc.titlePOTION: an end-to-end pipeline for positive Darwinian selection detection in genome-scale data through phylogenetic comparison of protein-coding genes.pt_BR
dc.typeArtigo de periódicopt_BR
dc.date.updated2016-06-22T11:11:11Zpt_BR
dc.subject.thesagroGenept_BR
dc.subject.thesagroFenótipopt_BR
dc.subject.thesagroPesquisapt_BR
dc.subject.nalthesaurusGenomicspt_BR
dc.subject.nalthesaurusPhylogenypt_BR
dc.subject.nalthesaurusGenespt_BR
dc.subject.nalthesaurusGenomept_BR
riaa.ainfo.id1027912pt_BR
riaa.ainfo.lastupdate2016-06-22pt_BR
dc.identifier.doi10.1186/s12864-015-1765-0pt_BR
dc.contributor.institutionJORGE A. HONGOpt_BR
dc.contributor.institutionGIOVANNI M. DE CASTROeng
dc.contributor.institutionLEANDRO CARRIJO CINTRA, CNPTIAeng
dc.contributor.institutionADHEMAR ZERLOTINI NETO, CNPTIAeng
dc.contributor.institutionFRANCISCO PEREIRA LOBO, CNPTIA.eng
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