Use este identificador para citar ou linkar para este item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1032178
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dc.contributor.authorLIMA, R. B. S.pt_BR
dc.contributor.authorSILVA, L. F. R. ept_BR
dc.contributor.authorMELO, M. R. S.pt_BR
dc.contributor.authorCOSTA, J. S.pt_BR
dc.contributor.authorPICANÇO, N. S.pt_BR
dc.contributor.authorLIMA, E. S.pt_BR
dc.contributor.authorVASCONCELLOS, M. C.pt_BR
dc.contributor.authorBOLETI, A. P. A.pt_BR
dc.contributor.authorSANTOS, J. M. P.pt_BR
dc.contributor.authorAMORIM, R. C. N.pt_BR
dc.contributor.authorCHAVES, F. C. M.pt_BR
dc.contributor.authorCOUTINHO, J. P.pt_BR
dc.contributor.authorTADEI, W. P.pt_BR
dc.contributor.authorKRETTLI, A. U.pt_BR
dc.contributor.authorPOHLIT, A. M.pt_BR
dc.date.accessioned2015-12-21T11:11:11Zpt_BR
dc.date.available2015-12-21T11:11:11Zpt_BR
dc.date.created2015-12-21pt_BR
dc.date.issued2015pt_BR
dc.identifier.citationMalaria Journal, v. 14, p. 1-14, Dec. 2015.pt_BR
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1032178pt_BR
dc.descriptionThe anti-malarials quinine and artemisinin were isolated from traditionally used plants (Cinchona spp. and Artemisia annua, respectively). The synthetic quinoline anti-malarials (e.g. chloroquine) and semi-synthetic artemisinin derivatives (e.g. artesunate) were developed based on these natural products. Malaria is endemic to the Amazon region where Plasmodium falciparum and Plasmodium vivax drug-resistance is of concern. There is an urgent need for new anti-malarials. Traditionally used Amazonian plants may provide new treatments for drug-resistant P. vivax and P. falciparum. Herein, the in vitro and in vivo antiplasmodial activity and cytotoxicity of medicinal plant extracts were investigated.pt_BR
dc.language.isoengeng
dc.rightsopenAccesseng
dc.subjectAntiplasmodialpt_BR
dc.subjectCytotoxicpt_BR
dc.subjectAndropogon leucostachyuspt_BR
dc.subjectXylopia amazonicapt_BR
dc.subjectZanthoxylum djalma-batistaept_BR
dc.titleIn vitro and in vivo anti-malarial activity of plants from the Brazilian Amazon.pt_BR
dc.typeArtigo de periódicopt_BR
dc.date.updated2016-03-01T11:11:11Zpt_BR
dc.subject.thesagroAnacardium Occidentalept_BR
dc.subject.thesagroPaullinia Cupanapt_BR
dc.subject.nalthesaurusCroton cajucarapt_BR
dc.subject.nalthesaurusPlasmodium falciparumpt_BR
dc.subject.nalthesaurusPlasmodium bergheipt_BR
dc.subject.nalthesaurusmalariapt_BR
riaa.ainfo.id1032178pt_BR
riaa.ainfo.lastupdate2016-03-01pt_BR
dc.identifier.doidoi:10.1186/s12936-015-0999-2pt_BR
dc.contributor.institutionRenata B. S. Lima; Luiz F. Rocha e Silva; Marcia R. S. Melo; Jaqueline S. Costa; Neila S. Picanço; Emerson S. Lima; Marne C. Vasconcellos; Ana Paula A. Boleti; Jakeline M. P. Santos; Rodrigo C. N. Amorim; FRANCISCO CELIO MAIA CHAVES, CPAA; Julia P. Coutinho; Wanderli P. Tadei, INPA; Antoniana U. Krettli; Adrian M. Pohlit.pt_BR
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