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dc.contributor.authorNERI, H. L.pt_BR
dc.contributor.authorPALHAO, M. P.pt_BR
dc.contributor.authorCOSTA, D. S.pt_BR
dc.contributor.authorVIANA, J. H. M.pt_BR
dc.contributor.authorFERNANDES, C. A. C.pt_BR
dc.date.accessioned2016-02-01T11:11:11Zpt_BR
dc.date.available2016-02-01T11:11:11Zpt_BR
dc.date.created2016-02-01pt_BR
dc.date.issued2015pt_BR
dc.identifier.citationReproduction in Domestic Animals, v. 50, n. 4, p. 692-695, 2015.pt_BR
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1035687pt_BR
dc.descriptionIntravaginal progesterone-releasing devices are largely used both as contraceptives in humans and as a component of oestrous synchronization protocols in cattle. To reduce costs in large-scale timed artificial insemination, the reuse of these releasing devices is common. Passive hormone diffusion, however, depends on the concentration gradient, which could affect the amount of residual progesterone present in these devices after a first use. To evaluate the effect of the presence of a corpus luteum in the release of progesterone from intravaginal devices, three synchronization protocols were designed to simulate the effects of inserting the device in the early dioestrus, late dioestrus or anoestrus. Holstein-Zebu cross-bred heifers were randomly allocated into one of these three treatments, and a series of blood samples was taken to evaluate the plasma progesterone concentrations. After 8 days, the intravaginal devices were removed and underwent a previously validated alcoholic extraction technique to measure the residual progesterone. Non-used devices were used as controls. As expected, the simultaneous presence of the intravaginal device and a corpus luteum resulted in increased plasma progesterone concentrations. Conversely, the amount of residual progesterone in the devices after use was inversely proportional to the plasma progesterone concentration. These results demonstrate that the release rate of progesterone from intravaginal devices is affected by the endogenous concentration of this hormone; consequently, the strategy for reuse should account for the category and expected luteal cyclic activity of the animals undergoing synchronization protocols.eng
dc.language.isoengeng
dc.rightsopenAccesseng
dc.subjectOestrous synchronizationpt_BR
dc.titleEndogenous progesterone concentrations affect progesterone release from intravaginal devices used for oestrous synchronization in cattle.pt_BR
dc.typeArtigo de periódicopt_BR
dc.date.updated2016-04-15T11:11:11Zpt_BR
dc.subject.nalthesaurusanimal reproductionpt_BR
dc.subject.nalthesaurusprogesteronept_BR
riaa.ainfo.id1035687pt_BR
riaa.ainfo.lastupdate2016-04-15pt_BR
dc.contributor.institutionH. L. Neri, UNIFENAS, MG; Hertape-Calier, Juatuba, MG; M. P. Palhao, UNIFENAS, MG; D. S. Costa, Universidade Federal do Mato Grosso do Sul; JOAO HENRIQUE MOREIRA VIANA, CNPGL; C. A. C. Fernandes, UNIFENAS.pt_BR
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