Título:	Risk factors for human Mycobacterium bovis infections in an urban area of Brazil.
Autoria:	SILVA, M. R. ROCHA, A. da S. ARAUJO, F. R. FONSECA-JÚNIOR, A. A. ALENCAR, A. P. de SUFFYS, P. N. COSTA, R. R. da MOREIRA, M. A. S. GUIMARÃES, M. D. C.
Afiliação:	MARCIO ROBERTO SILVA, CNPGL; Adalgiza da Silva Rocha, FIOCRUZ; FLABIO RIBEIRO DE ARAUJO, CNPGC; Antônio Augusto Fonseca-Júnior, MAPA / Pedro Leopoldo MG; Andrea Padilha de Alencar, MAPA /Pedro Leopoldo MG; Philip Noel Suffys, FIOCRUZ; Ronaldo Rodrigues da Costa, FHEMIG; Maria Aparecida Scatamburlo Moreira, UFV; Mark Drew Crosland Guimarães, UFMG.
Ano de publicação:	2018
Referência:	Memórias do Instituto Oswaldo Cruz, Rio de janeiro, v. 113, n. 8, 2018
Páginas:	6 p.
Conteúdo:	BACKGROUND The World Health Organization (WHO) has classified human zoonotic tuberculosis (TB) due to Mycobacterium bovis as a neglected issue in the developing world. In a recent cross-sectional study in Brazil, three of 189 TB patients presented with a coinfection of M. bovis and M. tuberculosis and were selected as cases for this study. OBJECTIVE The aim was to evaluate risk factors (RF) for zoonotic TB in an urban area of Brazil in order to guide preventive programmes. METHODS A matched case-control study was carried out nested within a cross-sectional study. For each of the three cases, 14 age- and sex-matched controls (TB due to M. tuberculosis) were selected. FINDINGS Zoonotic potential exposures (ZE) and extrapulmonary TB (EPTB) were independently associated with zoonotic TB in multivariate analyses. CONCLUSIONS ZE by occupation and consumption of raw milk and derivative products that place individuals in direct and indirect contact with animals and their excretions/secretions increase the risk for zoonotic TB in Brazil, especially among those with EPTB. Therefore, measures such as efficient control of bovine TB, distribution of pasteurised milk and its derivative products, and the diagnosis and monitoring of zoonotic TB in humans are essential steps, especially in developing countries where bovine TB is enzootic, and further studies are necessary.
NAL Thesaurus:	Tuberculosis Zoonoses Risk factors
Tipo do material:	Artigo de periódico
Acesso:	openAccess
Aparece nas coleções:	Artigo em periódico indexado (CNPGC)