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dc.contributor.authorCARRION, V. J.
dc.contributor.authorPÉREZ-JARAMILLO, J.
dc.contributor.authorCORDOVEZ, V.
dc.contributor.authorHOLLANDER, M. de
dc.contributor.authorTRACANNA, V.
dc.contributor.authorMENDES, L. W.
dc.contributor.authorMENDES, R.
dc.contributor.authorMEDEMA, M. H.
dc.contributor.authorRAAIJMAKERS, J. M.
dc.date.accessioned2019-01-11T00:11:11Z-
dc.date.available2019-01-11T00:11:11Z-
dc.date.created2019-01-10
dc.date.issued2018
dc.identifier.citationIn: PLANT MICROBIOME SYMPOSIUM, 2., 2018, Amsterdam. [Abstracts...] Amsterdam: Netherlands Institute of Ecology (NIOO-KNAW), 2018.
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1103500-
dc.descriptionEndophytic microbes have been proposed to contribute to a range of plant support functions, including nutrient acquisition and disease protection. To date, the molecular mechanisms underlying disease protection in the endosphere have only been studied for individual culturable organisms. Here, we conducted a systematic microbiome-wide perspective on the taxonomic diversity and functional potential of the endophytic microbiome of plants grown in an agricultural soil that is naturally suppressive to damping-off disease caused by the fungal root pathogen Rhizoctonia solani. Metagenomic analyses showed an enrichment of Burkholderiaceae, Chitinophagaceae and Xanthomonadaceae in the endosphere of plants grown in disease-suppressive soil challenged with the fungal root pathogen. Binning of the metagenomic sequences allowed de novo assembly of 25 high quality genomes of different endophytic bacterial genera. Subsequent trait-based analyses revealed numerous biosynthetic gene clusters (BGCs) overrepresented in the endophytic bacterial families of plants under fungal pathogen attack, including BGCs involved in signal transduction and antimicrobial activities, in particular nonribosomal peptides and polyketides. Network analyses further indicated that the traits enriched in the endophytic microbiome are multifactorial involving several novel BGCs encoding metabolites with yet unknown activities.
dc.language.isoporpt_BR
dc.rightsopenAccesspt_BR
dc.titleMining of the endophytic microbiome for novel biosynthetic genes and antifungal metabolites.
dc.typeResumo em anais e proceedings
dc.date.updated2019-01-11T00:11:11Zpt_BR
dc.subject.nalthesaurusMicrobiome
dc.subject.nalthesaurusAntifungal agents
dc.subject.nalthesaurusMetagenomics
riaa.ainfo.id1103500
riaa.ainfo.lastupdate2019-01-10
dc.contributor.institutionVictor J Carrion, Netherlands Institute of Ecology (NIOO-KNAW), Netherlands
dc.contributor.institutionJuan PÉREZ-JARAMILLO, Netherlands Institute of Ecology (NIOO-KNAW), Netherlandspt_BR
dc.contributor.institutionViviane Cordovez, Neethrlands Institutee of Ecology (NIOO-KNAW), Netherlandspt_BR
dc.contributor.institutionMattias de Hollander, Netherlands Institute of Ecology (NIOOKNAW), Netherlandspt_BR
dc.contributor.institutionMattias de Hollander, Wageningen University, Netherlandspt_BR
dc.contributor.institutionLucas W. Mendes, USPpt_BR
dc.contributor.institutionRODRIGO MENDES, CNPMApt_BR
dc.contributor.institutionMarnix H Medema, Wageningen University, Netherlandspt_BR
dc.contributor.institutionJos M. Raaijmakers, Netherlands Institute of Ecology (NIOO-KNAW), Netherlands.pt_BR
Aparece en las colecciones:Resumo em anais de congresso (CNPMA)

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