Use este identificador para citar ou linkar para este item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1113691
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dc.contributor.authorAMARAL, A. F.eng
dc.contributor.authorREBELATTO, R.eng
dc.contributor.authorKLEIN, C. S.eng
dc.contributor.authorTAKEUTI, K. L.eng
dc.contributor.authorOLIVEIRA FILHO, J. X. deeng
dc.contributor.authorMORES, N.eng
dc.contributor.authorCARDOSO, M. R. de I.eng
dc.contributor.authorBARCELLOS, D. E. S. N. deeng
dc.date.accessioned2019-10-31T18:14:46Z-
dc.date.available2019-10-31T18:14:46Z-
dc.date.created2019-10-31
dc.date.issued2019
dc.identifier.citationPesquisa Veterinária Brasileira, v. 39, n. 2, p. 107-111, 2019.eng
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1113691-
dc.descriptionAbstract: Pasteurella (P.) multocida is the causative agent of pneumonic pasteurellosis in swine, which is commonly associated with the final stages of enzootic pneumonia or porcine respiratory disease complex. Although this syndrome is one of the most common and important diseases of pigs, data on antimicrobial susceptibility of P. multocida isolates are uncommon in Brazil. Therefore, the present study was carried out to determine and to compare antimicrobial susceptibility profile of Brazilian P. multocida isolated from pigs with lesions of pneumonia or pleuritis during two-time periods. Historical isolates (period of 1981 to 1997; n=44) and recent isolates (period of 2011 to 2012; n=50) were used to determine the MIC of amoxicillin, enrofloxacin, florfenicol and tetracycline by microbroth dilution. Florfenicol had the lowest level of resistance for both historical and recent isolates (0% and 6%, respectively), while tetracycline had the highest (20.5% and 34%, respectively). Multi-drug resistance (MDR) to amoxicillin/florfenicol/tetracycline was observed in 6% of recent isolates. There was a significant increase (p?0.05) in resistance for amoxicillin and enrofloxacin in recent isolates compared with historic isolates (3.8% and 18%, respectively), most likely due to the selective pressure of antimicrobial usage to treat and prevent P. multocida infections. The results of this study showed an increase of isolates resistant to important drugs used in treatment of P. multocida infections in pigs, demonstrating the need for the implementation of rational use of antimicrobials in Brazilian swine industryeng
dc.language.isoengeng
dc.rightsopenAccesseng
dc.subjectAntimicrobial susceptibilityeng
dc.subjectBrazilian pigeng
dc.subjectMicrobroth dilutioneng
dc.subjectResistanceeng
dc.subjectPigseng
dc.subjectBacterioseseng
dc.subjectSuscetibilidade a antimicrobianoseng
dc.titleAntimicrobial susceptibility profile of historical and recent Brazilian pig isolates of Pasteurella multocida.eng
dc.typeArtigo de periódicoeng
dc.date.updated2019-10-31T18:14:46Z
dc.subject.thesagroSuínoeng
dc.subject.thesagroBacterioseeng
dc.subject.nalthesaurusSwineeng
dc.subject.nalthesaurusPasteurella multocida subsp. multocidaeng
dc.subject.nalthesaurusMinimum inhibitory concentrationeng
riaa.ainfo.id1113691eng
riaa.ainfo.lastupdate2019-10-31
dc.identifier.doi10.1590/1678-5150-PVB-5810eng
dc.contributor.institutionAMANDA F. AMARAL, North Caroline State University; RAQUEL REBELATTO, CNPSA; CATIA SILENE KLEIN, CNPSA; KARINE L. TAKEUTI, UFRGS; JOÃO XAVIER DE OLIVEIRA FILHO, UFRGS; NELSON MORES, CNPSA; MARISA RIBEIRO DE ITAPEMA CARDOSO, UFRGS; DAVID EMÍLIO SANTOS NEVES de BARCELLOS, UFRGS.eng
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