Use este identificador para citar ou linkar para este item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1123889
Registro completo de metadados
Campo DCValorIdioma
dc.contributor.authorDUARTE, D. S.
dc.contributor.authorNAASCIMENTO, J. A. de A.
dc.contributor.authorBRITTO, D. de
dc.date.accessioned2020-07-17T11:11:21Z-
dc.date.available2020-07-17T11:11:21Z-
dc.date.created2020-07-16
dc.date.issued2019
dc.identifier.citationCiência e Agrotecnologia, v. 43, e023819, 2019.
dc.identifier.issn1981-1829
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1123889-
dc.descriptionGiven the potentiality of nanoparticles (NP) to load substances as active principle of drugs, cosmetics and food, there is interest in increasing its production. Particularly in the agroindustrial area, the byproducts are source of functional compounds that must be stabilized by encapsulation, for example, to allow its application. Considering the amount of generated byproducts, it is necessary to understand the encapsulation synthesis in a high scale dimension. In this way, the active compounds vitamin C (from the byproduct of the acerola processing) and polyphenols (from the byproduct of grape processing) were nanoencapsulated into chitosan NP at three reactional volumes: 0.1; 1.0 and 10.0 dm3 . The NP were characterized for yield, particle size, morphology, encapsulation efficiency and release profile. In general, the increase in scale did not influence these parameters. It is found a close similarity for NP size value between the 0.1 and 10.0 dm3 reactional volumes. For example, for the blank control, the size was 155±6 and 227±118 nm respectively for 0.1 and 10.0 dm3 reactional volumes. Similarly for the encapsulated acerola byproduct extract (373±44 and 400±83 nm) and ascorbic acid (279±29 and 217±29 nm). For the encapsulated skin grape extract, the size decreased sharply from 1040 to 308 nm. The yield per volume ratio was about 1.3 mg cm-3. Additional analysis for NP with encapsulated skin grape extract, by Scanning Electronic Microscopy, showed uniformly distributed spherical structures and the release profile was similar for all reactional volumes. Thus, the system is suitable for scale-up for NP production.
dc.language.isoeng
dc.rightsopenAccesseng
dc.subjectPolifenóis
dc.subjectQuitosana
dc.subjectNanopartículas
dc.subjectAgroindustria
dc.subjectEncapsulamento
dc.titleScale-up in the synthesis of nanoparticles for encapsulation of agroindustrial active principles.
dc.typeArtigo de periódico
dc.subject.thesagroVitamina C
dc.subject.thesagroSubproduto
dc.subject.nalthesaurusVitamin content
dc.subject.nalthesaurusPolyphenols
dc.subject.nalthesaurusByproducts
riaa.ainfo.id1123889
riaa.ainfo.lastupdate2020-07-16
dc.identifier.doihttp://dx.doi.org/10.1590/1413-7054201943023819
dc.contributor.institutionDirliane Santos Duarte, UNIVASF; José Augusto de Almeida Nascimento, UFPE; DOUGLAS DE BRITTO, CPATSA.
Aparece nas coleções:Artigo em periódico indexado (CPATSA)

Arquivos associados a este item:
Arquivo Descrição TamanhoFormato 
Scale-up-in-the-synthesis-of-nanoparticles-2019.pdf711.12 kBAdobe PDFThumbnail
Visualizar/Abrir
Mostrar registro simples do item Visualizar estatísticas

FacebookTwitterDeliciousLinkedInGoogle BookmarksMySpace