Title:	Variants in myostatin and MyoD family genes are associated with meat quality traits in Santa Inês. sheep.
Authors:	SOUSA JUNIOR, L. P. B. MEIRA, A. N. AZEVEDO, H. C. MUNIZ, E. N. COUTINHO, L. L. MOURAO, G. B. LEAO, A. G. PEDROSA, V. B. PINTO, L. F. B.
Affiliation:	LUIS PAULO BATISTA SOUSA JUNIOR ARIANA NASCIMENTO MEIRA HYMERSON COSTA AZEVEDO, CPATC EVANDRO NEVES MUNIZ, CPATC LUIZ LEHMANN COUTINHO GERSON BARRETO MOURAO ANDRE GUSTAVO LEAO VICTOR BRENO PEDROSA LUIS FERNANDO BATISTA PINTO.
Date Issued:	2022
Citation:	Animal Biotechnology, v. 33, n. 2, p. 201-213, Apr. 2022.
Description:	Myostatin and MyoD family genes play vital roles in myogenesis and this study aimed to identify association of variants in MyoD1, MyoG, MyF5, MyF6, and MSTN genes with meat traits in Santa Inês sheep. A dataset with 44 variants and records of seven meat traits in 192 lambs (pH0, pH24, a, b, L, tenderness assessed by shear force, and water-holding capacity) was used. Single-locus and haplotype association analyses were performed, and the significance threshold was established according to Bonferroni?s method. Single-locus analysis revealed two associations at a Bonferroni level, where the variant c.935-185C > G in MyoD1 had an additive effect (4.31 ± 1.08 N) on tenderness, while the variant c.464 þ 185G > A in MyoG had an additive effect (2.86 ± 0.64) on a. Additionally, the haplotype replacement GT>AC in MSTN was associated with pH0 (1.26 ± 0.31), pH24 (1.07 ± 0.27), a (1.40 ± 0.51), and tenderness (3.83 ± 1.22 N), while the replacement GT > AG in MyoD1 was associated with pH0 (1.43 ± 0.26), pH24 (1.25 ± 0.22), b (1.06 ± 0.39), and tenderness (4.13 ± 1.16 N). Our results have demonstrated that some variants in MyoG, MyF6, MyoD1, and MSTN can be associated with physicochemical meat traits in Santa In^êes sheep.
Thesagro:	Ovino Ovinocultura Carne
NAL Thesaurus:	Sheep Lamb meat Lambs
Keywords:	Santa Inês
DOI:	https://doi.org/10.1080/10495398.2020.1781651
Notes:	Epub. 7 Jul. 2020.
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CPATC)