Título:	Innate immunity in chicken lines developed by Embrapa Suínos e Aves: antimicrobial activity of macrophages and serum.
Autoria:	SILVA, M. C. da COSTA, I. C. NAKAZATO, G. PINHEIRO, J. W. LEDUR, M. C. LOYOLA, W. VENANCIO, E. J.
Afiliação:	MIRIELE CAROLINE DA SILVA, UEL; IVETE CONCHON COSTA, UEL; GERSON NAKAZATO, UEL; JOÃO WAINE PINHEIRO, UEL; MONICA CORREA LEDUR, CNPSA; WAGNER LOYOLA, CNPSA; EMERSON JOSÉ VENANCIO, UEL.
Ano de publicação:	2021
Referência:	Revista Brasileira de Zootecnia, v. 50, n. e20200229, 2021.
Conteúdo:	Abstract: The objective of this study was to compare the antimicrobial activity of macrophages and serum in laying hen (MM, CC, and CCc) and broiler chicken lineages (TT and LL). Macrophages were evaluated for phagocytic and antimicrobial activity. Microbicidal serum activity was evaluated by the resistance test for serum and the agar test. The results showed that phagocytic activity was higher in males of the MM strain, with 13% of macrophages presenting phagocytosis, while the other lineages studied, and even female MM, presented a rate of 6% of phagocytic cells. However, antimicrobial activity in macrophages from males of CCc lineage and females of TT lineage were higher, eliminating more than 30% of the Salmonella enterica inoculum, while in the other strains, the results were similar, with inoculum reduction below 30%. In the serum resistance assay, female laying lines presented higher antibacterial activity than female broiler lines. In the trials to evaluate the microbicide activity of the serum, females of both broiler and laying lineages presented higher performance when compared with males of the same lineage. Females of laying hen lines (MM and CC) present a greater antibacterium activity than males. These results can contribute to a better understanding of the immune response in broiler chicken and laying hen lineages, to aid development of lineages of birds more resistant to pathogens
Thesagro:	Frango de Corte Poedeira Comercial Galinha Para Postura Ave Domestica Genética Animal Seleção Genética
NAL Thesaurus:	Broiler chickens Laying hens
Palavras-chave:	Imunidade natural Complement system Fowls Genetic selection Natural immunity
Digital Object Identifier:	https://doi.org/10.37496/rbz5020200229
Tipo do material:	Artigo de periódico
Acesso:	openAccess
Aparece nas coleções:	Artigo em periódico indexado (CNPSA)