Título:	The potential of novel gene editing-based approaches in forages and rumen Archaea for reducing livestock methane emissions.
Autoria:	SUBEDI, U. KADER, K. JAYAWARDHANE, K. N. POUDEL, H. CHEN, G. ACHARYA, S. CAMARGO, L. S. de A. BITTENCOURT, D. M. de C. SINGER, S. D.
Afiliação:	UDAYA SUBEDI, Lethbridge Research and Development Centre; KAZI KADER, Lethbridge Research and Development Centre; KETHMI N. JAYAWARDHANE, University of Alberta; HARI POUDEL, Lethbridge Research and Development Centre; GUANQUN CHEN, University of Alberta; SURYA ACHARYA, Lethbridge Research and Development Centre; LUIZ SERGIO DE ALMEIDA CAMARGO, CNPGL; DANIELA MATIAS DE C BITTENCOURT, Cenargen; STACY D. SINGER, Lethbridge Research and Development Centre.
Ano de publicação:	2022
Referência:	Agriculture, v. 12, n. 11, 1780, 2022.
Conteúdo:	Rising emissions of anthropogenic greenhouse gases such as carbon dioxide (CO2), nitrous oxide (N2O) and methane (CH4) are a key driver of climate change, which is predicted to have myriad detrimental consequences in coming years if not kept in check. Given the potency of CH4 in terms of trapping heat in the atmosphere in the short term, as well as the fact that ruminant production currently contributes approximately 30% of anthropogenic emissions, there is an impetus to substantially decrease the generation of ruminant-derived CH4. While various strategies are being assessed in this context, a multi-faceted approach is likely required to achieve significant reductions. Feed supplementation is one strategy that has shown promise in this field by attenuating methanogenesis in rumen archaea; however, this can be costly and sometimes impractical. In this review, we examine and discuss the prospect of directly modulating forages and/or rumen archaea themselves in a manner that would reduce methanogenesis using CRISPR/Cas-mediated gene editing platforms. Such an approach could provide a valuable alternative to supplementation and has the potential to contribute to the sustainability of agriculture, as well as the mitigation of climate change, in the future.
Thesagro:	Pecuária Bovino Efeito Estufa Gás Mudança Climática
NAL Thesaurus:	Climate change Environmental sustainability Greenhouse gas emissions Ruminants Livestock production
Digital Object Identifier:	https://doi.org/10.3390/agriculture12111780
Tipo do material:	Artigo de periódico
Acesso:	openAccess
Aparece nas coleções:	Artigo em periódico indexado (CNPGL)