Use este identificador para citar ou linkar para este item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1152824
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dc.contributor.authorMASSARIOLI, A. P.
dc.contributor.authorSARTORI, A. G. de O.
dc.contributor.authorJULIANO, F. F.
dc.contributor.authorAMARAL, J. E. P. G. do
dc.contributor.authorSANTOS, R. C. dos
dc.contributor.authorLIMA, L. M. de
dc.contributor.authorALENCAR, S. M. de
dc.date.accessioned2023-03-28T16:50:47Z-
dc.date.available2023-03-28T16:50:47Z-
dc.date.created2023-03-28
dc.date.issued2023
dc.identifier.citationFood Chemistry, v. 400, 134036, p. 1-8, 2023.
dc.identifier.issn2590-1575
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1152824-
dc.descriptionData concerning physiological recovery of whole peanut major phenolics throughout the gastrointestinal tract are scarce. In our study, the bioaccessibility and intestinal permeability of peanuts major phenolics were predicted by simulated digestion followed by Caco-2 cells monolayer model. Phenolics identification and quantification were performed by HPLC-ESI-QTOF-MS and HPLC-PDA, respectively. As results, p-coumaroyl conjugates with tartaric, sinapic and ferulic acids, and p-coumaric acid were the major phenolics found in the non-digested extract and in the digested and transported fractions. The in vitro bioaccessibility and Caco-2 cell transport of pcoumaric acid was 370% and 127%, respectively, while it was much lower for p-coumaroyl derivatives (7-100% and 14-31%, respectively). Nonetheless, the peroxyl scavenging activity remained unaltered, likely, at least artly, due to synergies between some phenolics, which concentration proportions changed throughout the experiment. Hence, there is indication that whole peanut is a source of bioavailable antioxidant phenolics.
dc.language.isoeng
dc.rightsopenAccess
dc.titleSimulated gastrointestinal digestion/Caco-2 cell model to predict bioaccessibility and intestinal permeability of p-coumaric acid and p-coumaroyl derivatives in peanut.
dc.typeArtigo de periódico
dc.subject.thesagroAmendoim
dc.subject.thesagroProteína Vegetal
dc.subject.thesagroNutrição Humana
dc.subject.thesagroÓleo Vegetal
dc.subject.nalthesaurusPhenolic compounds
dc.subject.nalthesaurusPeanuts
dc.subject.nalthesaurusArid zones
riaa.ainfo.id1152824
riaa.ainfo.lastupdate2023-03-28
dc.contributor.institutionADNA PRADO MASSARIOLI, ESALQ; ALAN GIOVANINI DE OLIVEIRA SARTORI, ESALQ; FERNANDA FRANCETTO JULIANO, ESALQ; JOSÉ EDUARDO PEDROSO GOMES DO AMARAL, ESALQ; ROSEANE CAVALCANTI DOS SANTOS, CNPA; LIZIANE MARIA DE LIMA, CNPA; SEVERINO MATIAS DE ALENCAR, ESALQ.
Aparece nas coleções:Artigo em periódico indexado (CNPA)

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