Título:	Whole-genome resequencing of common bean elite breeding lines.
Autoria:	SOUZA, I. P. de AZEVEDO, B. R. de COELHO, A. S. G. SOUZA, T. L. P. O. de VALDISSER, P. A. M. R. GOMES-MESSIAS, L. M. FUNICHELI, B. W. BRONDANI, C. VIANELLO, R. P.
Afiliação:	ISABELA PAVANELLI DE SOUZA, bolsista CNPAF; BEATRIZ ROSA DE AZEVEDO, bolsista CNPAF; ALEXANDRE SIQUEIRA GUEDES COELHO, UNIVERSIDADE FEDERAL DE GOIÁS; THIAGO LIVIO PESSOA OLIV DE SOUZA, CNPAF; PAULA ARIELLE M RIBEIRO VALDISSER, CNPAF; LUCAS MATIAS GOMES-MESSIAS, UNIVERSIDADE FEDERAL DE GOIÁS; BRENO OSVALDO FUNICHELI, UNIVERSIDADE FEDERAL DE SÃO CARLOS; CLAUDIO BRONDANI, CNPAF; ROSANA PEREIRA VIANELLO, CNPAF.
Ano de publicação:	2023
Referência:	Scientific Reports, v. 13, 12721, 2023.
Conteúdo:	The expansion of bean genome technologies has prompted new perspectives on generating resources and knowledge essential to research and implementing biotechnological tools for the practical operations of plant breeding programs. This study aimed to resequence the entire genome (whole genome sequencing?WGS) of 40 bean genotypes selected based on their significance in breeding programs worldwide, with the objective of generating an extensive database for the identification of single nucleotide polymorphisms (SNPs). Over 6 million SNPs were identified, distributed across the 11 bean chromosomes. After quality variant filtering, 420,509 high-quality SNPs were established, with an average of 38,228 SNPs per chromosome. These variants were categorized based on their predicted effects, revealing that the majority exerted a modifier impact on non-coding genome regions (94.68%). Notably, a significant proportion of SNPs occurred in intergenic regions (62.89%) and at least one SNP was identified in 58.63% of the genes annotated in the bean genome. Of particular interest, 7841 SNPs were identified in 85% of the putative plant disease defense-related genes, presenting a valuable resource for crop breeding efforts. These findings provide a foundation for the development of innovative and broadly applicable technologies for the routine selection of superior genotypes in global bean improvement and germplasm characterization programs.
Thesagro:	Feijão Genoma Melhoramento
NAL Thesaurus:	Genome Breeding lines Beans Genotype Breeding Single nucleotide polymorphism
ISSN:	2045-2322
Digital Object Identifier:	https://doi.org/10.1038/s41598-023-39399-6
Tipo do material:	Artigo de periódico
Acesso:	openAccess
Aparece nas coleções:	Artigo em periódico indexado (CNPAF)