Título:	Phytochemical characterization, antioxidant potential and antibacterial activity of the Croton argyrophylloides Muell. Arg. (Euphorbiaceae).
Autoria:	NERI, T. S. SILVA, K. W. L. MAIOR, L. P. S. SILVA, S. K. O. AZEVEDO, P. V. M. GOMES, D. C. S. SOUZA, M. A. PAVÃO, J. M. S. J. COSTA, J. G. da CUNHA, A. L. FERREIRA JÚNIOR, G. C. ROCHA, T. J. M. SANTOS, A. F. FONSECA, S. A.
Afiliação:	T. S. NERI, Centro Universitário Cesmac; K. W. L. SILVA, Centro Universitário Cesmac; L. P. S. MAIOR, Centro Universitário Cesmac; S. K. OLIVEIRA-SILVA, Centro Universitário Cesmac; P. V. M. AZEVEDO, Centro Universitário Cesmac; D. C. S. GOMES, Centro Universitário Cesmac; M. A. SOUZA, Centro Universitário Cesmac; J. M. S. J. PAVÃO, Centro Universitário Cesmac; JOAO GOMES DA COSTA, CNAT; A. L. CUNHA, Universidade Federal de Alagoas; G. C. FERREIRA-JÚNIOR, Instituto Federal de Educação, Ciência e Tecnologia do Acre; T. J. MATOS-ROCHA, Centro Universitário Cesmac, Universidade Estadual de Ciências da Saúde de Alagoas; A. F. SANTOS, Centro Universitário Cesmac, Universidade Estadual de Alagoas; S. A. FONSECA, Centro Universitário Cesmac.
Ano de publicação:	2023
Referência:	Brazilian Journal of Biology, v. 83, e236649, 2023.
Conteúdo:	Croton argyrophylloides Muell. Arg., from the Euphorbiaceae family, popularly known as marmeleiro prateado or sacatinga, is a plant from the Caatinga biome commonly found in Brazil?s northeastern region. The present study aimed to evaluate the antioxidant activity of the species. The phytochemical study was performed through qualitative analysis of chemical constituents and quantitative determination of the total phenol content through the Folin-Ciocalteu test. The qualitative and quantitative antioxidant tests were performed using the DPPH method (2.2 diphenyl-1-picryl hydrazil) and ferric reducing antioxidant power (FRAP). The minimum inhibitory concentration (MIC) was determined by microdilution in 96-well plates. The ethanolic extract of the leaves of C. argyrophylloides manifested antioxidant action in the quantitative DPPH test with a significant bioactivity of 84.70 AAO% in 500 µg/mL, with an EC50 of 236.79. The content of total phenolic compounds was 946.06 mg of gallic acid equivalents/g of sample, and total flavonoids was 58.11 mg of quercetin equivalents/g of sample, the result obtained for FRAP was 15294.44 µM Trolox/g of sample and ABTS was 718 μM Trolox of sample. The prospecting of the chemical constituents of the leaves of C. argyrophylloides revealed the presence of the main compounds that manifests the antioxidant activity and it was proven by the DPPH method that there is antioxidant activity in the analyzed sample, in addition to demonstrating a significant content of phenolic compounds and total flavonoid content in the species, which corroborates the antioxidant activity of the plant sample. The leaf extracts presented growth inhibition halos of 10 and 12 mm upon Staphylococcus aureus ATCC 25923.
NAL Thesaurus:	Antioxidants
Palavras-chave:	Croton argyrophylloides Muell Arg Phytochemistry Minimal inhibitory concentration
Digital Object Identifier:	https://doi.org/10.1590/1519-6984.236649
Tipo do material:	Artigo de periódico
Acesso:	openAccess
Aparece nas coleções:	Artigo em periódico indexado (CNAT)