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dc.contributor.authorBASSICHETO, M.
dc.contributor.authorOLIVEIRA, C.
dc.contributor.authorRIVERO, M.
dc.contributor.authorSIPOLONI, V.
dc.contributor.authorSOARES, J. K. C.
dc.contributor.authorSILVA, G. F. da
dc.contributor.authorJUSTO, G.
dc.contributor.authorVEIGA, T.
dc.contributor.authorSOMAN, L.
dc.date.accessioned2023-12-14T17:33:09Z-
dc.date.available2023-12-14T17:33:09Z-
dc.date.created2023-12-14
dc.date.issued2023
dc.identifier.citationIn: BRAZILIAN CONFERENCE ON NATURAL PRODUCT (BCNP), 9.
dc.identifier.citationMEETING ON MICROMOLECULAR EVOLUTION, SYSTEMATICS AND ECOLOGY (RESEM), 35., 2023, Salvador. Proceedings [...] Campinas: Galoá, 2023.eng
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1159736-
dc.descriptionChemical dereplication and genome mining approaches were applied to detect cytotoxic metabolites produced by P. limosum CMLD 19 with anticancer potential against human leukemia cells. During the ongoing study, metabolites such as fumitremorgin and triprostatin were detected in the rice extract of P. limosum which showed 80% of cell inhibition for different human leukemia cell lines.
dc.language.isoeng
dc.rightsopenAccess
dc.subjectCytotoxic metabolites
dc.subjectChemical dereplication
dc.titleDetection of antileukemia metabolites from P. limosum integrating genome mining, metabolomic analysis and cytotoxicity assays.
dc.typeResumo em anais e proceedings
dc.subject.nalthesaurusLeukemia
dc.subject.nalthesaurusGenome mining
riaa.ainfo.id1159736
riaa.ainfo.lastupdate2023-12-14
dc.contributor.institutionMILENA BASSICHETO, UNIVERSIDADE FEDERAL DE SÃO PAULO; CLÁUDIA OLIVEIRA, UNIVERSIDADE FEDERAL DE SÃO PAULO; MILENA RIVERO, UNIVERSIDADE FEDERAL DE SÃO PAULO; VICTOR SIPOLONI, UNIVERSIDADE FEDERAL DE SÃO PAULO; JULLIO KENNEDY CASTRO SOARES, UNIVERSIDADE FEDERAL DE SÃO PAULO; GILVAN FERREIRA DA SILVA, CPAA; GISELLE JUSTO, UNIVERSIDADE FEDERAL DE SÃO PAULO; THIAGO VEIGA, UNIVERSIDADE FEDERAL DE SÃO PAULO; LÍVIA SOMAN, UNIVERSIDADE FEDERAL DE SÃO PAULO.
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