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dc.contributor.authorSALMÓRIA, L. A.
dc.contributor.authorIBELLI, A. M. G.
dc.contributor.authorTAVERNARI, F. de C.
dc.contributor.authorPEIXOTO, J. de O.
dc.contributor.authorMORES, M. A. Z.
dc.contributor.authorMARCELINO, D. E. P.
dc.contributor.authorPINTO, K. D. S.
dc.contributor.authorCOLDEBELLA, A.
dc.contributor.authorSUREK, D.
dc.contributor.authorKAWSKI, V. L.
dc.contributor.authorLEDUR, M. C.
dc.date.accessioned2024-05-24T16:52:30Z-
dc.date.available2024-05-24T16:52:30Z-
dc.date.created2024-05-24
dc.date.issued2024
dc.identifier.citationAnimals, v. 14, n. 1407, 2024.
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1164461-
dc.descriptionCa and P homeostasis across the egg-laying cycle is a complex process involving absorption in the small intestine, reabsorption/excretion in the kidneys, and eggshell gland secretion. Diets with inadequate calcium and phosphorus can interfere with their absorption and digestibility, resulting in eggshell quality losses and reduced productive life, affecting egg production and welfare. A better understanding of gene expression profiles in the kidneys of laying hens during the late egg-laying period could clarify the renal role in mineral metabolism at this late stage. Therefore, the performance, egg quality and bone integrity-related traits, and expression profiles of kidney candidate genes were evaluated in 73-week-old laying hens receiving different Ca and P ratios in their diet: a high Ca/P ratio (HR, 22.43), a low ratio (LR, 6.71), and a medium ratio (MR, 11.43). The laying hens receiving the HR diet had improved egg production and eggshell quality traits compared to the other two groups. Humerus length was shorter in the HR than in the other groups. The CYP24A1 and TRPC3 genes were differentially expressed (p.adj ≤ 0.05) among the groups. Therefore, their expression profiles could be involved in calcium and phosphate transcellular transport in 73-week-old laying hens as a way to keep mineral absorption at adequate levels.
dc.language.isoeng
dc.rightsopenAccess
dc.subjectQualidade de ovos
dc.subjectQPCR
dc.subjectExpressão gênica
dc.subjectReação em cadeia da polimerase quantitativa
dc.titleCYP24A1 and TRPC3 gene expression in kidneys and their involvement in calcium and phosphate metabolism in laying hens.
dc.typeArtigo de periódico
dc.subject.thesagroGalinha Para Postura
dc.subject.thesagroPoedeira Comercial
dc.subject.thesagroSaúde
dc.subject.thesagroRim
dc.subject.thesagroCálcio
dc.subject.thesagroMineral
dc.subject.nalthesaurusEgg quality
dc.subject.nalthesaurusChickens
dc.subject.nalthesaurusQuantitative polymerase chain reaction
riaa.ainfo.id1164461
riaa.ainfo.lastupdate2024-05-24
dc.identifier.doihttps://doi.org/10.3390/ani14101407
dc.contributor.institutionLETÍCIA ALVES SALMÓRIA, UNIVERSIDADE ESTADUAL DO CENTRO-OESTE; ADRIANA MERCIA GUARATINI IBELLI, CPPSE; FERNANDO DE CASTRO TAVERNARI, CNPSA; JANE DE OLIVEIRA PEIXOTO, CNPSA; MARCOS ANTONIO ZANELLA MORES, CNPSA; DÉBORA ESTER PETRY MARCELINO, FACULDADE DE CONCÓRDIA; KARINE DAENQUELE SILVA PINTO, UNIVERSIDADE FEDERAL DE SÃO JOÃO DEL REI; ARLEI COLDEBELLA, CNPSA; DIEGO SUREK, GGPJ; VICKY LILGE KAWSKI, CNPSA; MONICA CORREA LEDUR, CNPSA.
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