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dc.contributor.authorGONÇALVES, F. F.
dc.contributor.authorSILVA, I. J. S.
dc.contributor.authorLOUREIRO, R. T.
dc.contributor.authorLIMA, J. M. S.
dc.contributor.authorANDRADE, S. L.
dc.contributor.authorSILVA, G. F. da
dc.contributor.authorPROCÓPIO, R. E. L.
dc.date.accessioned2024-10-04T14:54:19Z-
dc.date.available2024-10-04T14:54:19Z-
dc.date.created2024-10-04
dc.date.issued2024
dc.identifier.citationGenetics and Molecular Research, v. 23, n. 2, gmr19185, 2024.
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1167801-
dc.descriptionPlasmodium falciparum is an important parasite that causes malaria, which affects people in tropical and subtropical regions where it is an important public health problem. The genus Streptomyces is an important producer of antibiotics, in this context, the present work evaluates the antiplasmodial activity of Streptomyces isolated from sediments of the Madeira and Purus rivers. This activity was determined by using flow cytometry against the P. falciparum strain (FCR3), and by cytotoxicity tests on MRC5 and Vero cells. Streptomyces were able to inhibit P. falciparum FCR3 growth, with the best inhibition results obtained by the APUR32.5 and MPUR40.3 isolates.
dc.language.isoeng
dc.rightsopenAccess
dc.subjectAntimalarial
dc.subjectAntiplasmodial
dc.titleMetabolites from Streptomyces spp. isolated of Amazonian rivers against Plasmodium falciparum (FCR-3 strain).
dc.typeArtigo de periódico
dc.subject.nalthesaurusPlasmodium falciparum
dc.subject.nalthesaurusStreptomyces
dc.subject.nalthesaurusMalaria
riaa.ainfo.id1167801
riaa.ainfo.lastupdate2024-10-04
dc.identifier.doi10.4238/gmr19185
dc.contributor.institutionF. F. GONÇALVES, UNIVERSIDADE DO ESTADO DO AMAZONAS; I. J. S. SILVA; R. T. LOUREIRO, UNIVERSIDADE DO ESTADO DO AMAZONAS; J. M. S. LIMA, UNIVERSIDADE DO ESTADO DO AMAZONAS; S. L. ANDRADE, UNIVERSIDADE DO ESTADO DO AMAZONAS; GILVAN FERREIRA DA SILVA, CPAA; R. E. L. PROCÓPIO, UNIVERSIDADE DO ESTADO DO AMAZONAS.
Aparece en las colecciones:Artigo em periódico indexado (CPAA)

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