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dc.contributor.authorNESIYAMA, T. N. G.
dc.contributor.authorSANGALLI, J. R.
dc.contributor.authorBEM, T. H. C. de
dc.contributor.authorRECCHIA, K.
dc.contributor.authorMARTINS, S. M. M. K.
dc.contributor.authorANDRADE, A. F. C. de
dc.contributor.authorFERST, J. G.
dc.contributor.authorALMEIDA, G. H. D. R.
dc.contributor.authorMARQUES, M. G.
dc.contributor.authorDÓRIA, R. S. G.
dc.contributor.authorCARREGARO, A.
dc.contributor.authorFELICIANO, M.
dc.contributor.authorMIGLINO, M. A.
dc.contributor.authorBRESSAN, F. F.
dc.contributor.authorPERECIN, F.
dc.contributor.authorSILVEIRA, J. C.
dc.contributor.authorSMITH, L. C.
dc.contributor.authorBORDIGNON, V.
dc.contributor.authorMEIRELLES, F. V.
dc.date.accessioned2024-12-28T17:41:28Z-
dc.date.available2024-12-28T17:41:28Z-
dc.date.created2024-12-11
dc.date.issued2024
dc.identifier.citationAnimal Reproduction, v. 22, n. 1, ed. e20240037, 2024.
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1170411-
dc.descriptionAbstract: Somatic cell nuclear transfer (SCNT), or cloning, is used to reprogram cells and generate genetically identical embryos and animals. However, the cloning process is inefficient, limiting its application to producing valuable animals. In swine, cloning is mainly utilized to produce genetically modified animals. Indeed, recombinant DNA technologies have evolved considerably in recent years, with homologous recombination and gene editing technologies becoming more efficient and capable of recombining both alleles in a single cell. The selection of appropriate cells and their use as nuclear donors for SCNT is the most common method for generating edited and genetically modified animals for commercial and research purposes. This article reviews current applications of swine cloning and shares our personal experiences with the procedure in this species.
dc.language.isoeng
dc.rightsopenAccess
dc.subjectGenetically modified swine
dc.subjectSCNT
dc.titleSwine clones: potential application for animal production and animal models.
dc.typeArtigo de periódico
dc.subject.nalthesaurusCloning (animals)
dc.subject.nalthesaurusOocytes
dc.subject.nalthesaurusSomatic embryos
riaa.ainfo.id1170411
riaa.ainfo.lastupdate2024-12-11
dc.identifier.doihttps://doi.org/10.1590/1984-3143-AR2024-0037
dc.contributor.institutionTHAÍS NAOMI GONÇALVES NESIYAMA, UNIVERSIDADE DE SÃO PAULO; JULIANO RODRIGUES SANGALLI1, UNIVERSIDADE DE SÃO PAULO; TIAGO HENRIQUE CAMARA DE BEM, UNIVERSIDADE DE SÃO PAULO; KAIANA RECCHIA, UNIVERSIDADE DE SÃO PAULO; SIMONE MARIA MASSAMI KITAMURA MARTINS, UNIVERSIDADE DE SÃO PAULO; ANDRÉ FURUGEN CESAR DE ANDRADE, UNIVERSIDADE DE SÃO PAULO; JULIANA GERMANO FERST, UNIVERSIDADE DE SÃO PAULO; GUSTAVO HENRIQUE DONÁ RODRIGUES ALMEIDA, UNIVERSIDADE DE SÃO PAULO; MARIANA GROKE MARQUES, CNPSA; RENATA SAMPAIO GERMANO DÓRIA, UNIVERSIDADE DE SÃO PAULO; ADRIANO CARREGARO, UNIVERSIDADE DE SÃO PAULO; MARCUS FELICIANO, UNIVERSIDADE DE SÃO PAULO; MARIA ANGÉLICA MIGLINO, UNIVERSIDADE DE SÃO PAULO; FABIANA FERNANDES BRESSAN, UNIVERSIDADE DE SÃO PAULO; FELIPE PERECIN, UNIVERSIDADE DE SÃO PAULO; JULIANO COELHO DA SILVEIRA, UNIVERSIDADE DE SÃO PAULO; LAWRENCE CHARLES SMITH, UNIVERSITÉ DE MONTRÉAL; VILCEU BORDIGNON, MCGILL UNIVERSITY; FLÁVIO VIEIRA MEIRELLES, UNIVERSIDADE DE SÃO PAULO.
Appears in Collections:Artigo em periódico indexado (CNPSA)

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