Please use this identifier to cite or link to this item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1175537
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dc.contributor.authorOTON, L. F.eng
dc.contributor.authorRIBEIRO, P. R. V.eng
dc.contributor.authorBRITO, E. S. deeng
dc.contributor.authorSANTIAGO-AGUIAR, R. S. DEeng
dc.date.accessioned2025-05-13T18:48:40Z-
dc.date.available2025-05-13T18:48:40Z-
dc.date.created2025-05-13
dc.date.issued2025
dc.identifier.citationACS Omega, v. 10, n. 16, 16909−16920 2025.
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1175537-
dc.descriptionSoursop (Annona muricata L.) leaves are rich in bioactive compounds with promising pharmacological and food applications. Deep eutectic solvents (DESs), a class of green and tunable solvents, offer an efficient and sustainable alternative to their extraction. This study investigates the use of various DES formulations for extracting bioactive compounds from soursop leaves under optimized conditions, considering the temperature, solvent-to-biomass ratio, and extraction time in a solid–liquid system. Conventional techniques, such as magnetic stirring and ultrasonic bath extraction, were also evaluated for comparison. DESs were prepared using choline chloride and menthol as hydrogen bond acceptors (HBAs) combined with lactic acid, oxalic acid, and 1,2-propanediol as hydrogen bond donors (HBDs). The optimal extraction conditions were determined at 50 °C with a biomass-to-solvent ratio of 1:10 (m/v). Solvent performance and interactions with biomass were analyzed using NMR, FTIR, density, viscosity, pH, and total humidity assessments. Compared to water and ethanol, DESs exhibited superior efficiency and stability, enhancing cell wall disruption and improving extraction yields. Among the tested solvents, acidic DES (CCAO) demonstrated the highest extraction efficiency despite its high viscosity and density. These findings pave the way for future applications in the pharmaceutical and food industries, reinforcing DESs as a promising environmentally friendly alternative for the extraction of high-value bioactive compounds from plant biomass.
dc.language.isoeng
dc.rightsopenAccess
dc.titleSustainable Extraction of Bioactive Compounds from Annona muricata L. Leaves by Deep Eutectic Solvents (DESs).
dc.typeArtigo de periódico
dc.subject.thesagroAnnona Muricata
dc.subject.thesagroGraviola
dc.subject.nalthesaurusBioactive compounds
dc.subject.nalthesaurusExtraction
dc.subject.nalthesaurusMixtures
dc.subject.nalthesaurusSolvents
dc.subject.nalthesaurusMolecular biology
riaa.ainfo.id1175537
riaa.ainfo.lastupdate2025-05-13
dc.contributor.institutionLAIS F. OTON, FEDERAL UNIVERSTY OF CEARÁeng
dc.contributor.institutionPAULO RICELI VASCONCELOS RIBEIRO, CNPATeng
dc.contributor.institutionEDY SOUSA DE BRITO, CNATeng
dc.contributor.institutionRÍLVIA S. DE SANTIAGO-AGUIAR, FEDERAL UNIVERSITY OF CEARÁ.eng
Appears in Collections:Artigo em periódico indexado (CNPAT)

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