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dc.contributor.authorNEVES, K. O. G.
dc.contributor.authorSILVA, S. O.
dc.contributor.authorCRUZ, M. S.
dc.contributor.authorCHAVES, F. C. M.
dc.contributor.authorMACHADO, M. B.
dc.contributor.authorSANTOS, A. D. C.
dc.date.accessioned2025-10-13T14:48:34Z-
dc.date.available2025-10-13T14:48:34Z-
dc.date.created2025-10-13
dc.date.issued2025
dc.identifier.citationACS Omega, v. 10, n. 38, p. 44738-44748, 2025.
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1179613-
dc.descriptionEugenia punicifolia DC., a medicinal plant rich in bioactive phenolics, has shown promising results regarding its potential in the prevention of type 2 diabetes. This study investigated the seasonal influence on the chemical profile of leaf extracts (methanol:ethanol:water, 3:1:1) using 1H NMR spectroscopy and multivariate analysis. Principal component analysis (PCA) and partial least-squares discriminant analysis (PLS-DA) revealed distinct metabolic patterns associated with rainy (Feb-May), dry (Sep-Nov), and transitional (Jan, Jun, Jul, and Dec) periods. The PLS-DA model showed high predictive power (R2 > 0.85, Q2 > 0.85), identifying quercetin, myricetin, gallic acid, catechin, and epigallocatechin as seasonal markers. Significant correlations were found between metabolite levels and environmental variables, such as temperature, rainfall, and sunlight exposure. These results demonstrate that abiotic factors regulate the biosynthesis of phenolic compounds, reflecting the plant’s adaptive responses. The study offers a scientific basis for optimizing harvest timing and enhances understanding of the ecological and pharmacological potential of E. punicifolia, providing valuable insights into the development of standardized herbal medicines and phytoproducts.
dc.language.isoeng
dc.rightsopenAccess
dc.subjectPlants
dc.subjectEugenia punicifolia
dc.titleHow seasonality may shape key phenolic compounds of Eugenia punicifolia: a study driven by NMR Metabolomics.
dc.typeArtigo de periódico
dc.subject.thesagroPlanta Medicinal
dc.subject.nalthesaurusAntioxidants
dc.subject.nalthesaurusAromatic compounds
dc.subject.nalthesaurusFlavonoids
dc.subject.nalthesaurusGallic acid
dc.subject.nalthesaurusNuclear magnetic resonance spectroscopy
riaa.ainfo.id1179613
riaa.ainfo.lastupdate2025-10-13
dc.contributor.institutionKIDNEY O. G. NEVES, UNIVERSIDADE FEDERAL DO AMAZONAS; SAMUEL O. SILVA, UNIVERSIDADE FEDERAL DO AMAZONAS; MARINILDO S. CRUZ, UNIVERSIDADE FEDERAL DO AMAZONAS; FRANCISCO CELIO MAIA CHAVES, CPAA; MARCOS B. MACHADO, UNIVERSIDADE FEDERAL DO AMAZONAS; ALAN DIEGO C SANTOS, UNIVERSIDADE FEDERAL DE SANTA MARIA.
Aparece nas coleções:Artigo em periódico indexado (CPAA)

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