Título:	Comparative genomics of Sphingomonas from the cupuassu (Theobroma grandiflorum) phyllosphere reveals signatures of host adaptation and beneficial interactions.
Autoria:	SILVA, A. K. da PAULA, C. H. de MATOS, J. P. de RIBEIRO, D. F. CORDEIRO, I. F. LEMES, C. G. de C. SANCHEZ, A. B. GARCIA, C. C. M. ABREU, V. A. C. de ALVES, R. M. OLIVEIRA, M. de M. ALMEIDA, J. V. dos A. ALMEIDA, N. F. VARANI, A. M. MOREIRA, L. M.
Afiliação:	ANA KARLA DA SILVA, UNIVERSIDADE FEDERAL DE OURO PRETO; CAMILA HENRIQUES DE PAULA, UNIVERSIDADE FEDERAL DE OURO PRETO; JÉSSICA PEREIRA DE MATOS, UNIVERSIDADE FEDERAL DE OURO PRETO; DILSON FAGUNDES RIBEIRO, UNIVERSIDADE FEDERAL DE OURO PRETO; ISABELLA FERREIRA CORDEIRO, UNIVERSIDADE FEDERAL DE OURO PRETO; CAMILA GRACYELLE DE CARVALHO LEMES, UNIVERSIDADE FEDERAL DE OURO PRETO; ANGÉLICA BIANCHINI SANCHEZ, UNIVERSIDADE FEDERAL DE OURO PRETO; CAMILA CARRIÃO MACHADO GARCIA, UNIVERSIDADE FEDERAL DE OURO PRETO; VINICIUS A. C. DE ABREU, UNIVERSIDADE FEDERAL DO PARÁ; RAFAEL MOYSES ALVES, CPATU; MAURO DE MEDEIROS OLIVEIRA, UNIVERSIDADE ESTADUAL PAULISTA; JOÃO VICTOR DOS ANJOS ALMEIDA, UNIVERSIDADE ESTADUAL PAULISTA; NALVO F. ALMEIDA, UNIVERSIDADE FEDERAL DE MATO GROSSO DO SUL; ALESSANDRO M. VARANI, UNIVERSIDADE ESTADUAL PAULISTA; LEANDRO MARCIO MOREIRA, UNIVERSIDADE FEDERAL DE OURO PRETO.
Ano de publicação:	2026
Referência:	Symbiosis, 2026.
Conteúdo:	Members of the genus Sphingomonas are ubiquitous phyllosphere inhabitants recognized for their metabolic versatility and intimate associations with plants. Here, we describe and compare eight high-quality metagenome-assembled genomes (MAGs) of Sphingomonas recovered from leaves of the witches’-broom–resistant cupuassu (Theobroma grandiflorum) genotype C174. These MAGs represent four known species — S. adhaesiva (bin09, bin18, bin28), S. fennica (bin11), S. phyllospherae (bin08, bin10), and S. taxi (bin15, bin20) — and one novel lineage proposed as CandidatusSphingomonascupuassunensis. Comparative analyses with 15 reference Sphingomonasgenomes revealed a conserved core of 623 orthologous protein families and extensive genomic divergence, reflecting broad adaptive plasticity within the genus. Functional annotation uncovered substantial variability in xenobiotic degradation, nitrogen metabolism, secretion systems, and carbohydrate-active enzymes. Notably, genes encoding effector-related proteins, including avrXca, were identified in S. phyllospherae (bin08, bin10) and S. adhaesiva (bin09, bin28), suggesting potential immunomodulatory interactions with the host plant. Together, these findings highlight the genomic and functional diversity of Sphingomonas inhabiting the cupuassu phyllosphere and provide an evolutionary and ecological framework to explore their roles in tropical plant–microbe symbioses and host disease resilience.
Thesagro:	Cupuaçu Theobroma Grandiflorum Genoma Planta Hospedeira
NAL Thesaurus:	Sphingomonas
ISSN:	0334-5114.
Digital Object Identifier:	https://doi.org/10.1007/s13199-026-01124-y
Notas:	Online first.
Tipo do material:	Artigo de periódico
Acesso:	openAccess
Aparece nas coleções:	Artigo em periódico indexado (CPATU)