Por favor, use este identificador para citar o enlazar este ítem: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1187821
Registro completo de metadatos
Campo DCValorLengua/Idioma
dc.contributor.authorOKINO, C. H.
dc.contributor.authorBELLO, H. J. S.
dc.contributor.authorNICIURA, S. C. M.
dc.contributor.authorCUNHA, A. F. da
dc.contributor.authorCOSTA, E. C. da
dc.contributor.authorCAMPOS, E. M. de
dc.contributor.authorKAPRITCHKOFF, R. T. I.
dc.contributor.authorCORRÊA, L. G. P.
dc.contributor.authorMINHO, A. P.
dc.contributor.authorESTEVES, S. N.
dc.contributor.authorCHAGAS, A. C. de S.
dc.date.accessioned2026-06-25T13:48:57Z-
dc.date.available2026-06-25T13:48:57Z-
dc.date.created2026-06-25
dc.date.issued2026
dc.identifier.citationVeterinary research communication, v. 50, article number 372, 2026.
dc.identifier.issn1573-7446
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1187821-
dc.descriptionVariable resistance to Haemonchus contortus infection and the associated immune mechanisms have been investigated and characterized in different sheep breeds adapted to tropical climates. In a recent study, we compared the local immune responses of the resistant Santa Inês with those of the susceptible White Dorper and Texel sheep breeds under chronic haemonchosis, and evaluated the correlations of immune-related transcripts and different parasitic stages and sexes. The aim of present study was to further elucidate the immune mechanisms among these sheep breeds by comparing local responses, microscopic lesions in the abomasum and hematological parameters in lambs raised under varying levels of parasitic challenge. The naturally resistant Santa Inês breed maintained similar phenotypic characteristics across different levels of parasitic infection loads, whereas White Dorper and Texel breeds exhibited increased susceptibility under moderate to high challenge. Texel lambs showed altered mean corpuscular volume, indicative of macrocytic anemia, and also displayed the lowest resistance under low challenge conditions. Significantly higher levels of eosinophils, lymphocytes and monocytes in peripheral blood, along with increased expression of Galectin-11 gene in the abomasum, were observed in Santa Inês sheep compared to the other breeds. These responses may represent key host mechanisms contributing to improved control of infection. Overall, our findings demonstrate that resistance to H. contortus infection is breed-dependent and modulated by environmental parasite challenge, providing insights that may forward to the targeted strategies for sheep flock management.
dc.language.isoeng
dc.rightsopenAccess
dc.subjectHemogram
dc.subjectOvine
dc.subjectSanta Inês
dc.subjectRaca santa ines
dc.subjectWhite Dorper
dc.subjectRaça Texel
dc.titleSheep breed-specific response to environment challenge against Haemonchus contortus and effect on immuno-hematological parameters.
dc.typeArtigo de periódico
dc.subject.thesagroHaemonchus Contortus
dc.subject.thesagroOvino
dc.subject.thesagroInfecção
dc.subject.thesagroImunologia
dc.subject.thesagroCordeiro
dc.subject.nalthesaurusAbomasum
dc.subject.nalthesaurusHaemonchus
dc.subject.nalthesaurusGastrointestinal nematodes
dc.subject.nalthesaurusTexel
dc.subject.nalthesaurusInfection
riaa.ainfo.id1187821
riaa.ainfo.lastupdate2026-06-25
dc.identifier.doihttps://doi.org/10.1007/s11259-026-11304-2
dc.contributor.institutionCINTIA HIROMI OKINO, CPPSE; HORNBLENDA JOAQUINA SILVA BELLO, FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO; SIMONE CRISTINA MEO NICIURA, CPPSE; AMANDA FREITAS DA CUNHA, CENTRO UNIVERSITÁRIO CENTRAL PAULISTA; ESTEVÃO CAMILLO DA COSTA, CENTRO UNIVERSITÁRIO CENTRAL PAULISTA; EMANUELLE MARTINS DE CAMPOS, UNIVERSIDADE FEDERAL DE SÃO CARLOS; RAFAELA TAMI IKEDA KAPRITCHKOFF, UNIVERSIDADE ESTADUAL PAULISTA JÚLIO DE MESQUITA FILHO; LORRANE GABRIELE PINHEIRO CORRÊA, UNIVERSIDADE ESTADUAL PAULISTA JÚLIO DE MESQUITA FILHO; ALESSANDRO PELEGRINE MINHO, CPPSE; SÉRGIO NOVITA ESTEVES, CPPSE; ANA CAROLINA DE SOUZA CHAGAS, CPPSE.
Aparece en las colecciones:Artigo em periódico indexado (CPPSE)

Ficheros en este ítem:
Fichero TamañoFormato 
2026-cppse-artigo-cho-sheep-breed-specific-response-environment-challenge-against-haemonchus-contortus-effect-immuno-hematological-parameters.pdf1,95 MBAdobe PDFVisualizar/Abrir
Mostrar el registro sencillo del ítem

FacebookTwitterDeliciousLinkedInGoogle BookmarksMySpace