Por favor, use este identificador para citar o enlazar este ítem: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1188412
Registro completo de metadatos
Campo DCValorLengua/Idioma
dc.contributor.authorRODRIGUES, C. S.
dc.contributor.authorFARIA, D. A. de
dc.contributor.authorAZEVEDO, H. C.
dc.contributor.authorSILVA, K. de M.
dc.contributor.authorFACO, O.
dc.contributor.authorSANTOS, S. A.
dc.contributor.authorBRAGA, R. M.
dc.contributor.authorCAETANO, A. R.
dc.contributor.authorMORAES, J. C. F.
dc.contributor.authorSOUZA, C. J. H. de
dc.contributor.authorPAIVA, S. R.
dc.contributor.authorPIMENTEL, C. M. M.
dc.date.accessioned2026-07-20T11:53:05Z-
dc.date.available2026-07-20T11:53:05Z-
dc.date.created2026-07-20
dc.date.issued2026
dc.identifier.citationAnimals, v. 16, n. 13, 2008, 2026.
dc.identifier.issn2076-2615
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1188412-
dc.descriptionProlificacy and coat color are key economic traits influencing sheep production. This study evaluated a reduced panel of 48 SNPs previously associated with these traits and assessed its applicability to locally adapted Brazilian sheep breeds. A total of 1152 samples from 15 breeds, conserved in situ at conservation nuclei and ex situ in the Brazilian Animal Germplasm Bank, were genotyped. Allelic, genotypic, and haplotypic frequencies were estimated to compare genetic variability between in situ and ex situ populations. Additionally, linkage disequilibrium (LD) among SNPs within GDF9, a key gene associated with prolificacy, was evaluated across local breeds, revealing strong LD among specific markers. The results highlight the importance of the FecGE (GDF9) variant for prolificacy in hair sheep, confirming the presence of mutant allele E in prolific breeds, such as Santa Inês and Morada Nova, and identifying, for the first time, a high frequency of such allele in the Brazilian Blackbelly, which provides new insights into the genetic basis of this prolific hair breed. Other prolificacy-related genes, BMP15 and BMPR1B, appear to have no functional role in locally adapted breeds, as initially hypothesized, considering genetic differences among European and tropical sheep. Allelic and genotypic variation in ASIP, MC1R, TYRP1, and MITF genes reflected differences between wool and hair sheep and between local and commercial breeds. Overall, the results indicate that the germplasm bank effectively preserves in situ diversity. In conclusion, the reduced SNP panel efficiently genotyped Brazilian sheep for prolificacy and coat color SNPs, confirming which markers are present and segregating in these breeds. However, its utility could be improved by removing markers of limited relevance in the targeted breeds.
dc.language.isoeng
dc.rightsopenAccess
dc.titleAssessment of a Reduced SNP Panel Targeting Prolificacy and Coat Color Genes in Brazilian Sheep Breeds.
dc.typeArtigo de periódico
dc.subject.thesagroCor
dc.subject.thesagroPelo
dc.subject.thesagroGene
dc.subject.thesagroOvino
dc.subject.thesagroOvinocultura
dc.subject.nalthesaurusGenetic resources
dc.subject.nalthesaurusSheep breeds
dc.description.notesNa publicação Concepta McManus
riaa.ainfo.id1188412
riaa.ainfo.lastupdate2026-07-20
dc.identifier.doihttps://doi.org/10.3390/ani16132008
dc.contributor.institutionCAMILA SOUZA RODRIGUES, UNIVERSIDADE DE BRASÍLIA; DANIELLE ASSIS DE FARIA, UNIVERSIDADE DE BRASÍLIA; HYMERSON COSTA AZEVEDO, CPATC; KLEIBE DE MORAES SILVA, CNPC; OLIVARDO FACO, CNPC; SANDRA APARECIDA SANTOS, CPPSE; RAMAYANA MENEZES BRAGA, CPAF-RR; ALEXANDRE RODRIGUES CAETANO, CENARGEN; JOSE CARLOS FERRUGEM MORAES, CPPSUL; CARLOS JOSE HOFF DE SOUZA, CPPSUL; SAMUEL REZENDE PAIVA, CENARGEN; CONCEPTA MARGARET MCMANUS PIMENTEL, UNIVERSIDADE DE SÃO PAULO.
Aparece en las colecciones:Artigo em periódico indexado (CPATC)

Ficheros en este ítem:
Fichero TamañoFormato 
Assessment-of-a-Reduced-SNP-Panel.2026.pdf1,33 MBAdobe PDFVisualizar/Abrir
Mostrar el registro sencillo del ítem

FacebookTwitterDeliciousLinkedInGoogle BookmarksMySpace