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dc.contributor.authorBATISTA, E. M.
dc.contributor.authorVIANA, J. D. da R.
dc.contributor.authorAYALA-ZAVALA, J. F.
dc.contributor.authorBRUNO, L. M.
dc.contributor.authorOLIVEIRA, L. de S.
dc.date.accessioned2026-08-03T13:50:13Z-
dc.date.available2026-08-03T13:50:13Z-
dc.date.created2026-08-03
dc.date.issued2026
dc.identifier.citationDiversity, v. 18, n. 3, 185, Mar. 2026.
dc.identifier.issn1424-2818
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1188821-
dc.descriptionMedicinal plants from South and Central America are widely used, but the scientific literature remains fragmented and strongly concentrated in laboratory-based studies. This scientometric review mapped research trends and translational gaps for five focal species (Amburana cearensis, Libidibia ferrea, Justicia pectoralis, Lippia origanoides, and Spondias mombin). These species were selected because they combine ethnobotanical relevance, recurrent pharmacological and phytochemical interest, and sufficient representation in the retrieved corpus to support comparative scientometric analysis. Records indexed in the Web of Science Core Collection (1991–2024) were analyzed using VOSviewer and Bibliometrix within a transparent and reproducible workflow. Evidence was also organized across four domains, chemistry, preclinical, clinical, and safety, to support cross-species synthesis. A total of 183 publications were included. Brazil accounted for more than 60% of the records and concentrated the most productive authors and institutions. The Journal of Ethnopharmacology was the main publication outlet, followed by Industrial Crops and Products, indicating overlap between ethnopharmacological research and application-oriented development. Keyword networks were dominated by Spondias and Lippia, with recurring themes such as antioxidant activity, antimicrobial activity, and in vitro assays. Across species, preclinical evidence substantially exceeded controlled human studies and systematic safety reporting. Controlled trials were found only for Amburana and Justicia, whereas clinical and safety gaps remained evident for the other species despite the extensive experimental literature. Overall, the field is expanding, but its translational progress remains uneven. Future advances will depend on stronger chemical standardization, mechanism-driven study designs, and better integration of clinical and safety evidence.
dc.language.isoeng
dc.rightsopenAccess
dc.subjectScientometric analysis
dc.subjectEvidence gaps
dc.subjectEvidence mapping
dc.subjectResearch trends
dc.subjectTranslational research on medicinal plants
dc.subjectChemical standardization of plant extracts
dc.subjectPhytochemical markers
dc.subjectPreclinical evidence
dc.subjectClinical evidence
dc.subjectMedicinal plant safety
dc.subjectAntimicrobial activity
dc.subjectSouth and Central American medicinal plants
dc.subjectAmburana cearensis
dc.subjectLibidibia ferrea
dc.subjectJusticia pectoralis
dc.subjectAnálise cientométrica
dc.subjectAnálise bibliométrica
dc.subjectLacunas de evidência
dc.subjectMapeamento da evidência
dc.subjectTendências de pesquisa
dc.subjectPesquisa translacional em plantas medicinais
dc.subjectPadronização química de extratos vegetais
dc.subjectMarcadores fitoquímicos
dc.subjectEvidência pré-clínica
dc.subjectEvidência clínica
dc.subjectSegurança de plantas medicinais
dc.subjectAtividade antimicrobiana
dc.subjectAtividade antioxidante
dc.subjectCompostos bioativos
dc.subjectPlantas medicinais sul e centro-americanas
dc.titleResearch trends and evidence gaps in selected South/Central American medicinal plants: a scientometric review.
dc.typeArtigo de periódico
dc.subject.thesagroPlanta Medicinal
dc.subject.thesagroExtrato Vegetal
dc.subject.thesagroAntioxidante
dc.subject.thesagroCaesalpinia Férrea
dc.subject.thesagroLippia Sidoides
dc.subject.thesagroSpondias Mombin
dc.subject.nalthesaurusMedicinal plants
dc.subject.nalthesaurusPlant extracts
dc.subject.nalthesaurusPhytotherapy
dc.subject.nalthesaurusPharmacognosy
dc.subject.nalthesaurusEthnobotany
dc.subject.nalthesaurusPhytopharmaceuticals
dc.subject.nalthesaurusBibliometric analysis
dc.subject.nalthesaurusAntioxidant activity
dc.subject.nalthesaurusBioactive compounds
dc.subject.nalthesaurusLippia origanoides
riaa.ainfo.id1188821
riaa.ainfo.lastupdate2026-08-03
dc.identifier.doihttps://doi.org/10.3390/d18030185
dc.contributor.institutionELISABETH MARIANO BATISTA, UNIVERSIDADE FEDERAL DO CEARÁ; JOSÉ DIOGO DA ROCHA VIANA, UNIVERSIDADE FEDERAL DO CEARÁ; JESUS FERNANDO AYALA-ZAVALA, CENTRO DE INVESTIGACIÓN EN ALIMENTACIÓN Y DESARROLLO; LAURA MARIA BRUNO, CNPAT; LUCIANA DE SIQUEIRA OLIVEIRA, UNIVERSIDADE FEDERAL DO CEARÁ.
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