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dc.contributor.authorSOARES, I. L.
dc.contributor.authorSÁ, K.
dc.contributor.authorCANUTO, K. M.
dc.contributor.authorBANDEIRA, M. A.
dc.contributor.authorSALGUEIRO, L.
dc.contributor.authorZUZARTE, M.
dc.date.accessioned2026-08-07T10:47:44Z-
dc.date.available2026-08-07T10:47:44Z-
dc.date.created2026-08-06
dc.date.issued2026
dc.identifier.citationPlants, v. 15, n. 11, 1681, 2026.
dc.identifier.issn2223-7747
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/1189017-
dc.descriptionThis study evaluates the antifungal activity of Lippia gracilis Schauer essential oil traditionally used in northeastern Brazil for the treatment of skin disorders. The essential oil isolated from fresh leaves collected in Ceará, Brazil, was chemically characterized by GC–MS, showing a thymol-dominant profile (37.52%), accompanied by p-cymene (12.13%), γ-terpinene (9.29%), and gurjunene (10.95%). Antifungal assays revealed significant activity against several dermatophyte species with MIC and MFC values ranging from 50 to 100 μg/mL. Biofilm assays against Epidermophyton floccosum demonstrated strong inhibitory effects by disrupting biofilm formation, altering fungal morphology, and promoting in vitro skin cells migration, while also showing effective preventive effects in an ex vitro nail infection model. These findings support the potential of L. gracilis essential oil as a multifunctional natural antifungal agent for the management of refractory dermatophytosis and onychomycosis, and provide scientific validation for its traditional use in skin infection treatment.
dc.language.isoeng
dc.rightsopenAccess
dc.subjectCajueiro-anão ‘BRS 226
dc.subjectAdubação foliar complementar
dc.subjectÍndice relativo de clorofila (SPAD)
dc.subjectDesempenho fisiológico
dc.subjectProdutividade de castanha de caju
dc.subject‘BRS 226’ dwarf cashew
dc.subjectComplementary foliar fertilization
dc.subjectPhysiological performance
dc.subjectCashew nut yield
dc.titleMultifunctional activity of Lippia gracilis Schauer essential oil against skin infections.
dc.typeArtigo de periódico
dc.subject.thesagroCaju
dc.subject.thesagroAnacardium Occidentale
dc.subject.thesagroAdubação Foliar
dc.subject.thesagroNutrição Vegetal
dc.subject.thesagroFotossíntese
dc.subject.thesagroCastanha de Caju
dc.subject.nalthesaurusFoliar application
dc.subject.nalthesaurusPlant nutrition
dc.subject.nalthesaurusGas exchange
dc.subject.nalthesaurusStomatal conductance
dc.subject.nalthesaurusCrop yield
dc.subject.nalthesaurusCashew nuts
riaa.ainfo.id1189017
riaa.ainfo.lastupdate2026-08-06
dc.identifier.doihttps://doi.org/10.3390/plants15111681
dc.contributor.institutionIGOR LIMA SOARES, UNIVERSIDADE FEDERAL DO CEARÁ; KELLEN SÁ, UNIVERSIDADE FEDERAL DO CEARÁ; KIRLEY MARQUES CANUTO, CNPAT; MARY ANNE BANDEIRA, UNIVERSIDADE FEDERAL DO CEARÁ; LÍGIA SALGUEIRO, UNIVERSIDADE DE COIMBRA; MÓNICA ZUZARTE, UNIVERSIDADE DE COIMBRA.
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