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dc.contributor.authorLIU, G. E.
dc.contributor.authorLI, R. W.
dc.contributor.authorSONSTEGARD, T. S.
dc.contributor.authorMATUKUMALLI, L. K.
dc.contributor.authorSILVA, M. V. G. B.
dc.contributor.authorVAN TASSELL, C. P.
dc.date.accessioned2024-05-14T16:52:52Z-
dc.date.available2024-05-14T16:52:52Z-
dc.date.created2009-03-06
dc.date.issued2008
dc.identifier.citationAnimal Genetics, v. 39, n. 6, p. 655-658, 2008.
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/596819-
dc.descriptionWe present a detailed breakpoint mapping and population frequency analysis of a 214-kb microdeletion that removes multiple olfactory receptor genes. Using progressive rounds of PCR assays, we mapped the upstream and downstream breakpoints of this microdeletion event to 1 and 12 kb genomic regions, respectively. We developed PCR-based genotyping assays, characterized a dairy cattle panel of 96 samples and found that the frequency of the deletion allele was over 51%. Our results indicated that this microdeletion is an ancient event occurring in one of the earlier founders, and that it has been stably inherited across generations in the North American dairy cattle population.
dc.language.isoeng
dc.rightsopenAccess
dc.subjectBreakpoint
dc.subjectCattle genome
dc.subjectDeletion
dc.subjectPopulation frequency
dc.subjectStructural variants
dc.titleCharacterization of a novel microdeletion polymorphism on BTA5 in cattle.
dc.typeArtigo de periódico
riaa.ainfo.id596819
riaa.ainfo.lastupdate2024-05-14
dc.identifier.doihttps://doi.org/10.1111/j.1365-2052.2008.01769.x
dc.contributor.institutionG. E. Liu, USDA-ARS; R.W. LI, USDA-ARS; Tad S. Sonstegard USDA USA; Lakshmi Matukumalli George Mason University USA; Marcos Vinicius Gualberto Barbosa da Silva Embrapa Gado de Leite / USDA USA; Curtis Van Tassell USDA USA.
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