Title:	Genome-wide survey of SNP variation uncovers the genetic structure of cattle breeds.
Authors:	GIBBS, R. A. TAYLOR, J. F. VAN TASSELL, C. P. BARENDSE, W. EVERSOLE, K. A. GILL, C. A. GREEN, R. D. HAMERNIK, D. L. KAPPES, S. M. LIEN, S. MATUKUMALLI, L. K. MCEWAN, J. C. NAZARETH, L. V. SCHNABEL, R. D. WEINSTOCK, G. M. WHEELER, D. A. AJMONE-MARSAN, P. BOETTCHER, P. J. CAETANO, A. R. GARCIA, J. F. HANOTTE, O. MARIANI, P. SKOW, L. C. SONSTEGARD, T. S. WILLIAMS, J. L. DIALLO, B. HAILEMARIAM, L. MARTINEZ, M. L. MORRIS, C. A. SILVA, L. O. C. da SPELMAN, R. J. MULATU, W. ZHAO, K. ABBEY, C. A. AGABA, M. ARAUJO, F. R. BUNCH, R. J. BURTON, J. GORNI, C. OLIVIER, H. HARRISON, B. E. LUFF, B. MACHADO, M. A. MWAKAYA, J. PLASTOW, G. SIM, W. SMITH, T. THOMAZ, M. B. VALENTINI, A. WILLIAMS, P. WOMACK, J. WOOLLIAMS, J. A. LIU, Y. QIN, X. WORLEY, K. C. GAO, C. JIANG, H. MOORE, S. S. REN, Y. SONG, X.-Z. BUSTAMANTE, C. D. HERNANDEZ, R. D. MUZNY, D. M. PATIL, S. SAN LUCAS, A. FU, Q. KENT, M. P. VEGA, R. MATUKUMALLI, A. MCWILLIAM, S. SCLEP, G. BRYC, K. CHOI, J. GAO, H. GREFENSTETTE, J. J. MURDOCH, B. STELLA, A. VILLA-ANGULO, R. WRIGHT, M. AERTS, J. JANN, O. NEGRINI, R. GODDARD, M. E. HAYES, B. J. BRADLEY, D. G. SILVA, M. V. G. B. LAU, L. P. L. LIU, G. E. LYNN, D. J. PANZITTA, F. DODDS, K. G.
Affiliation:	RICHARD A. GIBBS JEREMY F. TAYLOR CURTIS P. VAN TASSELL WILLIAM BARENDSE KELLYE A. EVERSOLE CLARE A. GILL RONNIE D. GREEN DEBORA L. HAMERNIK STEVEN M. KAPPES SIGBJØRN LIEN LAKSHMI K. MATUKUMALLI JOHN C. MCEWAN LYNNE V. NAZARETH ROBERT D. SCHNABEL GEORGE M. WEINSTOCK DAVID A. WHEELER PAOLO AJMONE-MARSAN PAUL J. BOETTCHER ALEXANDRE R. CAETANO JOSE FERNANDO GARCIA OLIVIER HANOTTE PAOLA MARIANI LOREN C. SKOW TAD S. SONSTEGARD JOHN L. WILLIAMS BOUBACAR DIALLO LEMECHA HAILEMARIAM MARIO L MARTINEZ CHRIS A MORRIS LUIZ OTAVIO CAMPOS DA SILVA, CNPGC RICHARD J SPELMAN WOUDYALEW MULATU KEYAN ZHAO COLETTE A ABBEY MORRIS AGABA FLABIO RIBEIRO DE ARAUJO, CNPGC ROWAN J BUNCH JAMES BURTON CHIARA GORNI HANOTTE OLIVIER BLAIR E HARRISON BILL LUFF MARCO ANTONIO MACHADO, CNPGL JOEL MWAKAYA GRAHAM PLASTOW WARREN SIM TIMOTHY SMITH MERLE B THOMAS ALESSIO VALENTINI PAUL WILLIAMS JAMES WOMACK JOHN A WOOLLIAMS YUE LIU XIANG QIN KIM C WORLEY CHUAN GAO HUAIYANG JIANG STEPHEN S. MOORE YANRU REN XING-ZHI SONG CARLOS D. BUSTAMANTE RYAN D. HERNANDEZ DONNA M. MUZNY SHOBHA PATIL ANTHONY SAN LUCAS QING FU MATTHEW P. KENT RICHARD VEGA ARUNA MATUKUMALLI SEAN MCWILLIAM GERT SCLEP KATARZYNA BRYC JUNGWOO CHOI HONG GAO JOHN J. GREFENSTETTE BRENDA MURDOCH ALESSANDRA STELLA RAFAEL VILLA-ANGULO MARK WRIGHT JAN AERTS OLIVER JANN RICCARDO NEGRINI MIKE E. GODDARD BEN J. HAYES DANIEL G. BRADLEY MARCOS VINICIUS GUALBERTO B SILVA, CNPGL LILIAN P. L. LAU GEORGE E. LIU DAVID J. LYNN FRANCESCA PANZITTA KEN G. DODDS.
Date Issued:	2009
Citation:	Science, v. 324, n. 5926, p. 528-532, 2009.
Description:	The imprints of domestication and breed development on the genomes of livestock likely differ from those of companion animals. A deep draft sequence assembly of shotgun reads from a single Hereford female and comparative sequences sampled from six additional breeds were used to develop probes to interrogate 37,470 single-nucleotide polymorphisms (SNPs) in 497 cattle from 19 geographically and biologically diverse breeds. These data show that cattle have undergone a rapid recent decrease in effective population size from a very large ancestral population, possibly due to bottlenecks associated with domestication, selection, and breed formation. Domestication and artificial selection appear to have left detectable signatures of selection within the cattle genome, yet the current levels of diversity within breeds are at least as great as exists within humans.
Thesagro:	Genoma Melhoramento Genético Animal
Type of Material:	Artigo de periódico
Access:	openAccess
Appears in Collections:	Artigo em periódico indexado (CNPGL)