Use este identificador para citar ou linkar para este item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/864190
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dc.contributor.authorVENERONI, G. B.pt_BR
dc.contributor.authorMEIRELLES, S. L.pt_BR
dc.contributor.authorGROSSI, D. A.pt_BR
dc.contributor.authorGASPARIN, G.pt_BR
dc.contributor.authorIBELLI, A. M. G.pt_BR
dc.contributor.authorTIZIOTO, P. C.pt_BR
dc.contributor.authorOLIVEIRA, H. N.pt_BR
dc.contributor.authorALENCAR, M. M. dept_BR
dc.contributor.authorREGITANO, L. C. de A.pt_BR
dc.date.accessioned2011-04-10T11:11:11Zpt_BR
dc.date.accessioned2011-04-10T11:11:11Zpt_BR
dc.date.available2011-04-10T11:11:11Zpt_BR
dc.date.available2011-04-10T11:11:11Zpt_BR
dc.date.created2010-10-14pt_BR
dc.date.issued2010pt_BR
dc.identifier.citationGenetics and Molecular Research, v. 9, n. 4, p. 1997-2003, 2010.pt_BR
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/864190pt_BR
dc.descriptionCanchim is a composite cattle breed developed in Brazil for beef production. One of the breeding objectives is to increase fat deposition. QTLs for fat thickness and/or marbling have been reported on BTA4 and BTA14. The IGFBP3 and DDEF1 genes, mapped to BTA4 and BTA14, respectively, affect adipogenesis. We looked for SNPs in the IGFBP3 and DDEF1 genes that could be associated with backfat thickness in Canchim beef cattle. For SNP identification, sires with the highest accuracy were ranked according to expected breeding value for fat thickness; the 12 extremes (six sires with the highest and six with the lowest expected breeding value for the trait) were chosen. Six regions of the IGFBP3 and 14 regions of the DDEF1 were sequenced using the Sanger method. Nine SNPs were identified in IGFBP3 and 76 in the DDEF1. After an initial analysis, two SNPs were selected to be genotyped for the whole population;these were DDEF1g.279401A>G and IGFBP3c.4394T>C(Trp>Arg). We found a significant effect (P ? 0.05) of allele substitution on backfat thickness; however, the IGFBP3 SNP did not significantly affect this trait.pt_BR
dc.language.isoporpt_BR
dc.rightsopenAccesspt_BR
dc.subjectFat depositionpt_BR
dc.subjectCandidate genespt_BR
dc.subjectSNP identificationpt_BR
dc.titleProspecting candidate SNPs for backfat in Canchim beef cattle.pt_BR
dc.typeArtigo de periódicopt_BR
dc.date.updated2012-05-04T11:11:11Zpt_BR
riaa.ainfo.id864190pt_BR
riaa.ainfo.lastupdate2012-05-04pt_BR
dc.contributor.institutionGISELE B. VENERONI, UFSCar/SÃO CARLOS, SPpt_BR
dc.contributor.institutionSARAH L. MEIRELLES, UFSCar/SÃO CARLOS, SPpt_BR
dc.contributor.institutionD. A. GROSSI, UFSCar/SÃO CARLOS, SPpt_BR
dc.contributor.institutionGUSTAVO GASPARIN, UFSCar/SÃO CARLOS, SPpt_BR
dc.contributor.institutionADRIANA M. G. IBELLI, UFSCar/SÃO CARLOS, SPpt_BR
dc.contributor.institutionUFSCar/SÃO CARLOS, SPpt_BR
dc.contributor.institutionHENRIQUE NUNES OLIVEIRA, UNESP DE JABOTICABAL, SPpt_BR
dc.contributor.institutionMAURICIO MELLO DE ALENCAR, CPPSEpt_BR
dc.contributor.institutionLUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.pt_BR
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