Título:	Somatic development and embryo yield in crossbred F1 mice generated by different mating strategies.
Autoria:	BATISTA, R. I. T. P. WOHLRES-VIANA, S. PINTO, I. S. B. MAFFILI, V. V. VIANA, J. H. M.
Afiliação:	RIBRIO IVAN TAVARES PEREIRA BATISTA, CES-JF; SABINE WOHLRES-VIANA, UFJF; ISABELA SILVESTRE BARRETO PINTO, UFV; VITOR V. MAFFILI, FIOCRUZ; JOAO HENRIQUE MOREIRA VIANA, CNPGL.
Ano de publicação:	2010
Referência:	Brazilian Journal of Biology, v. 70, n. 1, p. 145-149, 2010.
Conteúdo:	The aim of this study was to evaluate different mating strategies among endogamic strains to create F1 populations of mice, minimising the effect of inbreeding depression on somatic development and embryo yield. Females from the strains Swiss, CBA and C57Bl/6 were divided in nine experimental mate arrangements. The total numbers of pups born alive per dam and somatic development, estimated by weighing and measuring the crown-rump length, were recorded. Superovulation response was evaluated in outbreed females. Litter size differed among endogamic dams, irrespective of the sire. Somatic development results suggest heterosis and imprinting phenomena, once a differential parental effect was demonstrated. There was no difference in corpora lutea, ova or embryos recovered (P > 0.05), but recovery and viability rates differ among F1 groups (P < 0.05). The association of dam prolificity with somatic development and superovulation response of the pups should be considered for experimental F1 populations establishment. The use of outbreed animals, however, did not reduce response variability to hormone treatment.
NAL Thesaurus:	mice strains
Palavras-chave:	Embryo Endogamy Imprinting
Digital Object Identifier:	https://doi.org/10.1590/S1519-69842010000100020
Tipo do material:	Artigo de periódico
Acesso:	openAccess
Aparece nas coleções:	Artigo em periódico indexado (CNPGL)