Por favor, use este identificador para citar o enlazar este ítem: http://www.alice.cnptia.embrapa.br/alice/handle/doc/937283
Registro completo de metadatos
Campo DCValorLengua/Idioma
dc.contributor.authorRAMOS, C. A. N.pt_BR
dc.contributor.authorARAUJO, F. R.pt_BR
dc.contributor.authorALVES, L. C.pt_BR
dc.contributor.authorSOUZA, I. I. F. dept_BR
dc.contributor.authorGUEDES JUNIOR, D. S.pt_BR
dc.contributor.authorSOARES, C. O.pt_BR
dc.date.accessioned2012-10-19T11:11:11Zpt_BR
dc.date.available2012-10-19T11:11:11Zpt_BR
dc.date.created2012-10-19pt_BR
dc.date.issued2012pt_BR
dc.identifier.citationVeterinary Parasitology, v. 187, n. 3-4, p. 548-552, julho, 2012.pt_BR
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/937283pt_BR
dc.descriptionBovine babesiosis caused by Babesia bovis remains an important constraint for the development of cattle industries worldwide. Effective control can be achieved by vaccination with live attenuated phenotypes of the parasite. However, these vaccines have a number of drawbacks, which justifies the search for better, safer vaccines. In recent years, a number of parasite proteins with immunogenic potential have been discovered. However, there is little information on the genetic conservation of these proteins among different parasite isolates, which hinders their assessment as immunogens. The aim of the present study was to evaluate the conservation of the genes ama-1, acs-1, rap-1, trap, p0 and msa2c among five Brazilian isolates of B. bovis. Through polymerase chain reaction, genetic sequencing and bioinformatics analysis of the genes, a high degree of conservation (98?100%) was found among Brazilian isolates of B. bovis and the T2Bo isolate. Thus, these genes are worth considering as viable candidates to be included in a recombinant cocktail vaccine for cattle babesiosis caused by B. bovis.pt_BR
dc.language.isoporpt_BR
dc.rightsopenAccesspt_BR
dc.subjectGenetic conservationpt_BR
dc.subjectVaccinept_BR
dc.titleGenetic conservation of potentially immunogenic proteins among Brazilian isolates of Babesia bovis.pt_BR
dc.typeArtigo de periódicopt_BR
dc.date.updated2012-10-19T11:11:11Zpt_BR
dc.subject.thesagroBabesia bovispt_BR
dc.subject.nalthesaurusBrazilpt_BR
riaa.ainfo.id937283pt_BR
riaa.ainfo.lastupdate2012-10-19pt_BR
dc.contributor.institutionCARLOS A.N. RAMOS, Bolsista CNPGC; FLABIO RIBEIRO ARAUJO, CNPGC; LEUCIO C. ALVES, Laboratório de Doenc¸ as Parasitárias dos Animais Domésticos, Departamento de Medicina Veterinária –UFRPE, Recife, PE; INGRID IEDA FERNANDO DE SOUZA, Bolsista CNPGC; DANIEL S. GUEDES JUNIOR, BolsistaCNPGC; CLEBER OLIVEIRA SOARES, CNPGC.pt_BR
Aparece en las colecciones:Artigo em periódico indexado (CNPGC)

Ficheros en este ítem:
Fichero Descripción TamañoFormato 
2012Babesiagenoma.pdf519.14 kBAdobe PDFVista previa
Visualizar/Abrir

FacebookTwitterDeliciousLinkedInGoogle BookmarksMySpace