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dc.contributor.authorGEORGE, S.pt_BR
dc.contributor.authorCIRCLE, K.pt_BR
dc.contributor.authorLINDBLOM, S.pt_BR
dc.contributor.authorVILAIN, S.pt_BR
dc.contributor.authorROSA, A. J. de M.pt_BR
dc.contributor.authorFRANCIS, D.pt_BR
dc.contributor.authorBRÖZEL, V.pt_BR
dc.contributor.authorKAUSHIK, R. S.pt_BR
dc.date.accessioned2012-11-23T11:11:11Zpt_BR
dc.date.available2012-11-23T11:11:11Zpt_BR
dc.date.created2012-11-23pt_BR
dc.date.issued2012pt_BR
dc.identifier.citationJournal of Clinical and Cellular Immunology, v. 3, issue 3, 2012.pt_BR
dc.identifier.issn2155-9899pt_BR
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/940452pt_BR
dc.descriptionIt has been suggested that changes in diet at weaning in pigs induce intestinal inflammation which may be mediated through toll-like receptors (TLRs). We hypothesized that the use of antibiotics as growth promoters and subsequent changes in intestinal microbiota may mediate changes in the expression of TLRs in the intestine. Thus, this study was performed to assess the changes in intestinal TLRs in weanling pigs in response to the use of chlortetracycline as a growth promotant, and under gnotobiotic conditions. Eighteen cesarean-derived half-sib piglets were divided into three groups; antibiotic-fed, control (normal-fed) and gnotobiotic groups.TLR-2, -4, -5 and -9 gene expression and abundance of TLR-2 and -9 proteins in the ileum of pigs was assessed at 5 wk of age. No significant differences (p ?0.5) in TLR-2, -4, -5 and -9transcript levels and abundanceof TLR-2 and -9 proteins among three groups of pigswere observed.eng
dc.language.isoengeng
dc.rightsopenAccesseng
dc.titleAssessment of toll-like receptors in the ileum of weanling pigs - responses to feed antibiotic chlortetracycline and gnotobiotic conditions.pt_BR
dc.typeArtigo de periódicopt_BR
dc.date.updated2012-12-05T11:11:11Zpt_BR
dc.subject.thesagroGenéticapt_BR
dc.subject.nalthesaurusToll-like receptorseng
dc.subject.nalthesaurusIleumeng
dc.subject.nalthesaurusChlortetracyclineeng
dc.format.extent28 p.eng
riaa.ainfo.id940452pt_BR
riaa.ainfo.lastupdate2012-12-05pt_BR
dc.contributor.institutionSAJAN GEORGE, SOUTH DAKOTA STATE UNIVERSITY; KATHERINE CIRCLE, SOUTH DAKOTA STATE UNIVERSITY; STACY LINDBLOM, SOUTH DAKOTA STATE UNIVERSITY; SEBASTIEN VILAIN, SOUTH DAKOTA STATE UNIVERSITY; ARTUR JORDAO DE MAGALHAES ROSA, CPAC; DAVID FRANCIS, SOUTH DAKOTA STATE UNIVERSITY; VOLKER BRÖZEL, SOUTH DAKOTA STATE UNIVERSITY; RADHEY S. KAUSHIK, SOUTH DAKOTA STATE UNIVERSITY.pt_BR
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