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dc.contributor.authorSILVA, F. F. ept_BR
dc.contributor.authorRESENDE, M. D. V. dept_BR
dc.contributor.authorROCHA, G. S.pt_BR
dc.contributor.authorDUARTE, D. A. S.pt_BR
dc.contributor.authorLOPES, P. S.pt_BR
dc.contributor.authorBRUSTOLIN, O. J. B.pt_BR
dc.contributor.authorTHUS, S.pt_BR
dc.contributor.authorVIANA, J. M. S.pt_BR
dc.contributor.authorGUIMARÃES, S. E. F.pt_BR
dc.date.accessioned2014-03-21T11:11:11Zpt_BR
dc.date.available2014-03-21T11:11:11Zpt_BR
dc.date.created2014-03-21pt_BR
dc.date.issued2013pt_BR
dc.identifier.citationGenetics and Molecular Biology, v. 36, n. 4, p. 520-527, 2013.pt_BR
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/983083pt_BR
dc.descriptionIn the current post-genomic era, the genetic basis of pig growth can be understood by assessing SNP marker effects and genomic breeding values (GEBV) based on estimates of these growth curve parameters as phenotypes. Although various statistical methods, such as random regression (RR-BLUP) and Bayesian LASSO (BL), have been applied to genomic selection (GS), none of these has yet been used in a growth curve approach. In this work, we compared the accuracies of RR-BLUP and BL using empirical weight-age data from an outbred F2 (Brazilian Piau X commercial) population. The phenotypes were determined by parameter estimates using a nonlinear logistic regression model and the halothane gene was considered as a marker for evaluating the assumptions of the GS methods in relation to the genetic variation explained by each locus. BL yielded more accurate values for all of the phenotypes evaluated and was used to estimate SNP effects and GEBV vectors. The latter allowed the construction of genomic growth curves, which showed substantial genetic discrimination among animals in the final growth phase. The SNP effect estimates allowed identification of the most relevant markers for each phenotype, the positions of which were coincident with reported QTL regions for growth traits.pt_BR
dc.language.isoengeng
dc.rightsopenAccesseng
dc.subjectMelhoramento genéticopt_BR
dc.titleGenomic growth curves of an outbred pig population.pt_BR
dc.typeArtigo de periódicopt_BR
dc.date.updated2015-02-18T11:11:11Zpt_BR
dc.subject.thesagroCurva de Crescimentopt_BR
dc.subject.thesagroPorcopt_BR
riaa.ainfo.id983083pt_BR
riaa.ainfo.lastupdate2015-02-18pt_BR
dc.contributor.institutionFABIANO FONSECA E SILVA, UFV; MARCOS DEON VILELA DE RESENDE, CNPF; GILSON SILVÉRIO ROCHA, UVF; DARLENE ANA S. DUARTE, UFV; PAULO SÁVIO LOPES, UFV; OTÁVIO J. B. BRUSTOLIN, UFV; SANDER THUS, WAGENINGEN UNIVERSITY; JOSÉ MARCELO S. VIANA, UFV; SIMONE E. F. GUIMARÃES, UFV.pt_BR
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