Use este identificador para citar ou linkar para este item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/998406
Registro completo de metadados
Campo DCValorIdioma
dc.contributor.authorSOMAVILLA, A. L.
dc.contributor.authorSONSTEGARD, T. S.
dc.contributor.authorHIGA, R. H.
dc.contributor.authorROSA, A. do N.
dc.contributor.authorSIQUEIRA, F.
dc.contributor.authorSILVA, L. O. C. da
dc.contributor.authorTORRES JUNIOR, R. A. de A.
dc.contributor.authorCOUTINHO, L. L.
dc.contributor.authorMUDADU, M. de A.
dc.contributor.authorALENCAR, M. M. de
dc.contributor.authorREGITANO, L. C. de A.
dc.date.accessioned2022-11-16T20:01:19Z-
dc.date.available2022-11-16T20:01:19Z-
dc.date.created2014-10-24
dc.date.issued2014
dc.identifier.citationAnimal Genetics, v. 45, n. 6, p. 771-781, dec. 2014
dc.identifier.urihttp://www.alice.cnptia.embrapa.br/alice/handle/doc/998406-
dc.descriptionBrazilian Nellore cattle (Bos indicus) have been selected for growth traits for over more than four decades. In recent years, reproductive and meat quality traits have become more important because of increasing consumption, exports and consumer demand. The identification of genome regions altered by artificial selection can potentially permit a better understanding of the biology of specific phenotypes that are useful for the development of tools designed to increase selection efficiency. Therefore, the aims of this study were to detect evidence of recent selection signatures in Nellore cattle using extended haplotype homozygosity methodology and BovineHD marker genotypes (>777 000 single nucleotide polymorphisms) as well as to identify corresponding genes underlying these signals. Thirty-one significant regions (P < 0.0001) of possible recent selection signatures were detected, and 19 of these overlapped quantitative trait loci related to reproductive traits, growth, feed efficiency, meat quality, fatty acid profiles and immunity. In addition, 545 genes were identified in regions harboring selection signatures. Within this group, 58 genes were associated with growth, muscle and adipose tissue metabolism, reproductive traits or the immune system. Using relative extended haplotype homozygosity to analyze high-density single nucleotide polymorphism marker data allowed for the identification of regions potentially under artificial selection pressure in the Nellore genome, which might be used to better understand autozygosity and the effects of selection on the Nellore genome.
dc.language.isoeng
dc.rightsopenAccess
dc.subjectSingle nucleotid
dc.subjectRelative extended haplotype homozygosity
dc.subjectSingle nucleotide polymorphisms
dc.titleA genome-wide scan for selection signatures in Nellore cattle.
dc.typeArtigo de periódico
dc.subject.thesagroBos Indicus
dc.subject.nalthesaurusbeef cattle
dc.subject.nalthesaurusgenotyping
dc.subject.nalthesauruslinkage disequilibrium
riaa.ainfo.id998406
riaa.ainfo.lastupdate2022-11-16
dc.identifier.doi10.1111/age.12210
dc.contributor.institutionA. L. SOMAVILLA, Programa de Pós-Graduação em Genética e Melhoramento Animal, UNESP/FCAV, Jaboticabal, Brasil; T. S. SONSTEGARD, Bovine Functional Genomics Laboratory, ANRI, USDA-ARS, Beltsville, MD, USA; ROBERTO HIROSHI HIGA, CNPTIA; ANTONIO DO NASCIMENTO ROSA, CNPGC; FABIANE SIQUEIRA, CNPGC; LUIZ OTAVIO CAMPOS DA SILVA, CNPGC; ROBERTO AUGUSTO DE A TORRES JUNIOR, CNPGC; L. L. COUTINHO, Escola Superior de Agricultura Luiz de Queiroz (Esalq), USP, Piracicaba, Brasil; MAURICIO DE ALVARENGA MUDADU, CPPSE; MAURICIO MELLO DE ALENCAR, CPPSE; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE.
Aparece nas coleções:Artigo em periódico indexado (CPPSE)

Arquivos associados a este item:
Arquivo TamanhoFormato 
PROCI-2014.00083-2.pdf540,41 kBAdobe PDFVisualizar/Abrir
Mostrar registro simples do item Visualizar estatísticas

FacebookTwitterDeliciousLinkedInGoogle BookmarksMySpace