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|Title:||Assessing signatures of selection through variation in linkage disequilibrium between taurine and indicine cattle.|
|Authors:||O'BRIEN, A. M. P.|
UTSUNOMIYA, Y. T.
BICKHART, D. M.
LIU, G. E.
TASSEL, C. P. V.
SONSTEGARD, T. S.
SILVA, M. V. G. B.
GARCIA, J. F.
|Affiliation:||ANA M. PÉREZ O'BRIEN, University of Natural Resources and Life Sciences, Vienna; YURI T. UTSUNOMIYA, UNESP; GÁBOR MÉSZÁROS, University of Natural Resources and Life Sciences, Vienna; DEREK M BICKHART, ARS-USDA, USA; GEORGE E. LIU, ARS-USDA, USA; CURTIS P. VAN TASSEL, ARS-USDA, USA; TAD S. SONSTEGARD, ARS-USDA, USA; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; JOSÉ F. GARCIA, UNESP; JOHANN SÖLKNER, University of Natural Resources and Life Sciences, Vienna.|
|Citation:||Genetics Selection Evolution, v. 46, n. 19, 2014.|
|Description:||Signatures of selection are regions in the genome that have been preferentially increased in frequency and fixed in a population because of their functional importance in specific processes. These regions can be detected because of their lower genetic variability and specific regional linkage disequilibrium (LD) patterns. By comparing the differences in regional LD variation between dairy and beef cattle types, and between indicine and taurine subspecies, we aim at finding signatures of selection for production and adaptation in cattle breeds. The VarLD method was applied to compare the LD variation in the autosomal genome between breeds, including Angus and Brown Swiss, representing taurine breeds, and Nelore and Gir, representing indicine breeds. The conclusions are that VarLD method is a powerful tool to identify differences in linkage disequilibrium between cattle populations and putative signatures of selection with potential adaptive and productive importance.|
|NAL Thesaurus:||linkage disequilibrium|
|Keywords:||Cattle - genetic improvement|
Minor allele frequency.
|Type of Material:||Separatas|
|Appears in Collections:||Artigo em periódico indexado (CNPGL)|
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