Please use this identifier to cite or link to this item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1032282
Research center of Embrapa/Collection: Embrapa Informática Agropecuária - Resumo em anais de congresso (ALICE)
Date Issued: 2015
Type of Material: Resumo em anais de congresso (ALICE)
Authors: FULAZ, S. F.
CABRINI, F.
TASIC, L.
BORRO, L.
NESHICH, G.
Additional Information: STEPHANIE F. FULAZ; FLÁVIA CABRINI; LJUBICA TASIC; LUIZ BORRO; GORAN NESHICH, CNPTIA.
Title: Computational biology tools in design of an agrochemical against Xyllela fastidiosa.
Publisher: In: CONGRESSO DE INICIAÇÃO CIENTIFICA DA UNICAMP, 33., 2015, Campinas. [Proceedings...]. Campinas: Unicamp, 2015.
Language: en
Keywords: Bioinformática
PilT
Ferramentas de biologia computacional
Computational biology tools
Biology.
Description: Xylella fastidiosa is a Gram-negative, non-flagellated bacterium that causes CVC in citrus and Pierce?s disease in grapevines. The CVC affects 40% of the 200 million orange trees in São Paulo state. It colonizes the xylem vessels of the plants, blocking the water and nutrient flows. PilT protein is a part of the motility system and very important for Xyllela pathogenicity and our protein target for drug design. Computational biology tools were used to design the compound able to inhibit the formation of the PilT hexamer, leading to loss of Xyllela pathogenicity. This approach could be employed in the development of new inhibitors against different targets belonging to the same protein family of PilT.
Thesagro: Xylella Fastidiosa.
NAL Thesaurus: Bioinformatics.
Data Created: 2015-12-22
Appears in Collections:Resumo em anais de congresso (CNPTIA)

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