Please use this identifier to cite or link to this item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/890878
Title: Tuberculin skin testing in HIV-infected patients in Campo Grande, Mato Grosso do Sul State, Brazil.
Authors: OLIVEIRA, S. M. V. L. de
PANIAGO, A. M. M.
BONECINI-ALMEIDA, M. G.
BERTONI, N.
STABILE, A. C.
CUNHA, R. V. da
OLIVEIRA, O. A. de
DRUZIAN, A. F.
NEGRI, A. C.
ANDREOTTI, R.
Affiliation: UFMS; UFMS; FIOCRUZ; FIOCRUZ; ANHANGUERA-UNIDERP; UFMS; UFMS; UFMS; UFMS; RENATO ANDREOTTI E SILVA, CNPGC.
Date Issued: 2010
Citation: Journal of Venomous Animals and Toxins including Tropical Diseases, Botucatu, v.16 no.2, p.285-297, May 2010.
Description: A cross-sectional study on HIV/AIDS was carried out in 108 outpatients from the university hospital of the Federal University of Mato Grosso do Sul, Campo Grande, Brazil, from July to December 2008, to investigate latent tuberculosis infection using the tuberculin skin test (TST). The prevalence of positive results was 13.9%. The CD4+ T cell count (p = 0.091) and the diagnosis time (p = 0.010) were statistically significant when compared with TST positivity. In the cohort of HIV/AIDS patients who had latent tuberculosis infection, the median diagnosis time was eight years. Undetectable viral load presented significant association (p = 0.046) with tuberculosis infection. The fact that numerous individuals with HIV/AIDS infection presented a negative reaction to the tuberculin skin test is probably related to alterations in the cellular immune response induced by HIV infection. The tuberculin test is a useful tool for the detection of latent tuberculosis infection and should be performed in all HIV/AIDS individuals at the time of the diagnosis and on a yearly basis, if negative. Both the early identification of the tuberculosis infection by the tuberculin skin test at the moment of immunological restoration and chemoprophylaxis in infected individuals are mechanisms to control HIV/AIDS and tuberculosis coinfection.
Thesagro: Tuberculose.
Keywords: Teste tuberculínico
AIDS
HIV
Saúde humana.
Language: en
Type of Material: Separatas
Access: openAccess
Appears in Collections:Artigo em periódico indexado (CNPGC)

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