Please use this identifier to cite or link to this item: http://www.alice.cnptia.embrapa.br/alice/handle/doc/952025
Research center of Embrapa/Collection: Embrapa Florestas - Artigo em periódico indexado (ALICE)
Date Issued: 2012
Type of Material: Artigo em periódico indexado (ALICE)
Authors: CUNICO, M. M.
AUER, C. G.
LIMA, C. P. de
CÔCCO, L. C.
YAMAMOTO, C. I.
MIGUEL, M. D.
MIGUEL, O. G.
SANQUETTA, C. R.
Additional Information: MIRIAM MACHADO CUNICO, UFPR; CELSO GARCIA AUER, CNPF; CRISTINA PEITZ DE LIMA, UFPR; LILIAN CRISTINA CÔCCO, UFPR; CARLOS ITSUO YAMAMOTO, UFPR; MARILIS DALLARMI MIGUEL, UFPR; OBDULIO GOMES MIGUEL, UFPR; CARLOS ROBERTO SANQUETTA, UFPR.
Title: Bioautography to assess antibacterial activity of Ottonia martiana Miq. (Piperaceae) on the human oral microbiota.
Publisher: Revista de Ciências Farmacêuticas Básica e Aplicada, v. 33, n. 4, p. 515-519, 2012.
Language: en
Keywords: Atividade antibacteriana
Dor de dente
Ottonia martiana.
Description: Ottonia martiana Miq. (Piperaceae), a plant known popularly in southern Brazil as “anestésia” and used in the treatment of odontalgia for its anesthetic action on the oral mucosa, was investigated for antibacterial activity by paper disc agar diffusion and bioautographic methods, against microorganisms present in the human oral cavity [Streptococcus mutans (ATCC 25175), Streptococcus mitis (ATCC 49456), Streptococcus pyogenes (ATCC 19615), Streptococcus salivarius (ATCC 25975), Escherichia coli (ATCC 11229 and 25922), Pseudomonas aeruginosa (ATCC 27853) and Enterobacter aerogenes (ATCC 27853).The crude extract of O. martiana (32.9 mg mL-1) had antibacterial potential against all Gram-positive bacteria tested. Analysis of the bioautograms led to the detection of bioactive substances, among which it was possible to identify piperovatine (Rf 0.35), piperlonguminine (Rf 0.52) and isopiperlonguminine (Rf 0.52). The piperovatine and isopiperlonguminine were isolated from the roots of O. martiana, guided by a bioautographic antibacterial bioassay.
Thesagro: Amido.
Data Created: 2013-03-04
Appears in Collections:Artigo em periódico indexado (CNPF)

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